Results 101 to 110 of about 2,130,795 (350)

Fused Analytical and Iterative Reconstruction (AIR) via modified proximal forward-backward splitting: a FDK-based iterative image reconstruction example for CBCT

open access: yes, 2016
This work is to develop a general framework, namely analytical iterative reconstruction (AIR) method, to incorporate analytical reconstruction (AR) method into iterative reconstruction (IR) method, for enhanced CT image quality and reconstruction ...
Gao, Hao
core   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

HighDimMixedModels.jl: Robust high-dimensional mixed-effects models across omics data.

open access: yesPLoS Computational Biology
High-dimensional mixed-effects models are an increasingly important form of regression in which the number of covariates rivals or exceeds the number of samples, which are collected in groups or clusters.
Evan Gorstein   +2 more
doaj   +1 more source

Accurate Reaction-Diffusion Operator Splitting on Tetrahedral Meshes for Parallel Stochastic Molecular Simulations [PDF]

open access: yesJournal of Chemical Physics, 2015
Spatial stochastic molecular simulations in biology are limited by the intense computation required to track molecules in space either in a discrete time or discrete space framework, which has led to the development of parallel methods that can take ...
Iain Hepburn, Weiliang Chen, E. Schutter
semanticscholar   +1 more source

Control of reaction-diffusion equations on time-evolving manifolds

open access: yes, 2016
Among the main actors of organism development there are morphogens, which are signaling molecules diffusing in the developing organism and acting on cells to produce local responses. Growth is thus determined by the distribution of such signal. Meanwhile,
Duteil, Nastassia Pouradier   +3 more
core   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

An innovative analytical method utilizing aboodh residual power series for solving the time-fractional newell-whitehead-segel equation [PDF]

open access: yesComputational Algorithms and Numerical Dimensions
In this study, we use a new method called Abode Residual Power Series Method (ARPSM) to derive the analytical results of the Newell-Whitehead-Siegel equation.
Seyed Edalatpanah, Eisa Abdolmaleki
doaj   +1 more source

Dispersion operators and resistant second-order functional data analysis [PDF]

open access: yes, 2017
Inferences related to the second-order properties of functional data, as expressed by covariance structure, can become unreliable when the data are non-Gaussian or contain unusual observations. In the functional setting, it is often difficult to identify
Kraus, David, Panaretos, Victor M.
core  

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

An open-source FACS automation system for high-throughput cell biology.

open access: yesPLoS ONE
Recent advances in gene editing are enabling the engineering of cells with an unprecedented level of scale. To capitalize on this opportunity, new methods are needed to accelerate the different steps required to manufacture and handle engineered cells ...
Diane M Wiener   +12 more
doaj   +1 more source

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