Results 41 to 50 of about 52,735 (283)
OPGs and pandemic legacy [PDF]
British Dental Journal, 2021 A, Regan, T, Walker
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Advanced Science, EarlyView.A hierarchical CM/LDH nanoplatform integrates ROS‐scavenging Ce‐MOF nanozymes with acid‐neutralizing CaAl‐LDH and is delivered within GelMA hydrogel to diabetic bone defects. By remodeling the oxidative‐acidic microenvironment, preserving mitochondrial homeostasis, and suppressing mtDNA–cGAS–STING inflammatory signaling, CM/LDH reduces proinflammatory ...
Xu Chen +10 more
wiley +1 more source
DataSheet1_Delayed denervation-induced muscle atrophy in Opg knockout mice.DOCX
, 2023 Recent evidence has shown a crucial role for the osteoprotegerin/receptor activator of nuclear factor κ-B ligand/RANK (OPG/RANKL/RANK) signaling axis not only in bone but also in muscle tissue; however, there is still a lack of understanding of its ...
Licheng Zhang (590322) +8 more
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Advanced Science, EarlyView.Schematic illustration of the mechanism by which ZIF‐90@PU alleviates osteoporosis via H3K18la‐mediated NFATc1 pathway suppression. ABSTRACT Osteoporosis is characterized by dysregulated osteoclast activity, leading to excessive bone resorption and structural damage.
Jiajia Lu +5 more
wiley +1 more source
Pharmaceutics, 2020 Osteoprotegerin (OPG) serum levels are associated with liver fibrogenesis and have been proposed as a biomarker for diagnosis. However, the source and role of OPG in liver fibrosis are unknown, as is the question of whether OPG expression responds to ...
Adhyatmika Adhyatmika +14 more
doaj +1 more source
Role of osteoprotegerin (OPG) in cancer
Clinical Science, 2006 OPG (osteoprotegerin), a secreted member of the TNF (tumour necrosis factor) receptor superfamily, has a variety of biological functions which include the regulation of bone turnover. OPG is a potent inhibitor of osteoclastic bone resorption and has been investigated as a potential therapeutic for the treatment of both osteoporosis and tumour-induced ...
Holen, I, Shipman, C
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Advanced Science, EarlyView.This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang +9 more
wiley +1 more source
Interactions of porphyromonas gingivalis with bone marrow cells: implications on mediators of bone resorption [PDF]
, 2012 PhDPeriodontitis is a multi-factorial disease characterised by the loss of connective tissue and underlying alveolar bone leading to the loss of teeth. Porphyromonas gingivalis (P.
Reddi, Durga
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Foreign body in the tongue as a result of accidental gunshot from hunting rifle
Journal of Education, Health and Sport, 2019 Gunshots are one of the many causes of urgent admission of patients due to necessity of removing foreign bodies and bleeding control. A 63 y.o. patient was referred to the Department of Oral Surgery due to an accidental gunshot, which occurred in early ...
Monika Ratajek-Gruda +2 more
doaj +1 more source
Stem Cell Research & Therapy, 2021 Introduction Osthole has a potential therapeutic application for anti-osteoporosis. The present study verified whether osthole downregulates osteoclastogenesis via targeting OPG.
Zhen-Xiong Jin +5 more
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