Results 51 to 60 of about 52,735 (283)

Delayed denervation-induced muscle atrophy in Opg knockout mice

Frontiers in Physiology, 2023
Recent evidence has shown a crucial role for the osteoprotegerin/receptor activator of nuclear factor κ-B ligand/RANK (OPG/RANKL/RANK) signaling axis not only in bone but also in muscle tissue; however, there is still a lack of understanding of its ...
Mingming Zhang, Mingming Zhang, Ming Chen, Ming Chen, Yi Li, Yi Li, Man Rao, Man Rao, Duanyang Wang, Zhongqi Wang, Zhongqi Wang, Licheng Zhang, Licheng Zhang, Pengbin Yin, Pengbin Yin, Peifu Tang, Peifu Tang   +16 more
doaj   +1 more source

PIAS3 CircRNA‐Loaded Lipid Nanoparticles Restore ALOX15 SUMOylation to Suppress Cementoblast Ferroptosis and Attenuate Orthodontically Induced Root Resorption

Advanced Science, EarlyView.
Orthodontic compression suppresses PIAS3 expression in cementoblasts, impairing ALOX15 SUMOylation and ubiquitin‐mediated degradation, which leads to ALOX15 accumulation, lipid peroxidation, ferroptosis, and osteoclastogenesis. Local delivery of PIAS3 circRNA‐loaded lipid nanoparticles restores the PIAS3–ALOX15 regulatory pathway, alleviates ...
Yifei Hou, Chongzheng Yan, Xinrui Xu, Zihan Yang, Xinhui Wu, Hongxu Zhao, Xuan Song, Jianing Zhang, Yijing Li, Aohua Yang, Xiamei Lu, Yi Liu   +11 more
wiley   +1 more source

RANKL/OPG ratio regulates odontoclastogenesis in damaged dental pulp

Scientific Reports, 2021
Bone-resorbing osteoclasts are regulated by the relative ratio of the differentiation factor, receptor activator NF-kappa B ligand (RANKL) and its decoy receptor, osteoprotegerin (OPG).
Daisuke Nishida, Atsushi Arai, Lijuan Zhao, Mengyu Yang, Yuko Nakamichi, Kanji Horibe, Akihiro Hosoya, Yasuhiro Kobayashi, Nobuyuki Udagawa, Toshihide Mizoguchi   +9 more
doaj   +1 more source

Association of bone mineral density and CTx with B cell OPG expression (%), B cell RANKL expression (%), RANKL/OPG ratio and Log RANKL/OPG ratio.

, 2014
rs  =  Spearman rank correlation coefficient. Significant outcomes are in bold.Association of bone mineral density and CTx with B cell OPG expression (%), B cell RANKL expression (%), RANKL/OPG ratio and Log RANKL/OPG ratio.
Cecile Delille (659671), M. Neale Weitzmann (243386), Jeffrey L. Lennox (353341), Kehmia Titanji (659670), Andrea Knezevic (659673), Kirk A. Easley (659674), Sara E. Sanford (318929), Aswani Vunnava (367208), Antonina Foster (659672), Ighovwerha Ofotokun (659675), Anandi N. Sheth (353335)   +10 more
core   +1 more source

Exposure to heat waves and drought improves subsequent leaf heat tolerance for five oak species in southern California

American Journal of Botany, EarlyView.
Abstract Premise Given the threats of climate change, we investigated the impact of high temperatures separately and in combination with reduced soil water on leaf heat tolerance for five oaks (Fagaceae) with overlapping ranges in southern California, USA: Quercus agrifolia and Q. chrysolepis (evergreen species), Q. douglasii and Q.
Casey D. Wisely, G. Olivia Plumb, Mira N. Ranganath, Emily Dolida, Ishan Ashford, Graham Luethe, Tim Thibault, Gretchen B. North   +7 more
wiley   +1 more source

From the Church, With the Church, and For the Church: Another Look at the Significance of Parachurch for Church Growth

Veritas: Jurnal Teologi dan Pelayanan, 2023
This article discusses parachurch (hereinafter referred to as the Organisasi Pendamping Gereja / OPG). According to Jerry White, a parachurch is all forms of spiritual ministry whose organizational structure is not under the control of the church ...
Tommy Indarto
doaj   +1 more source

Association of RANKL and OPG genotypes with their serum levels and RANKL/OPG ratio.

, 2015
A, B. Soluble RANKL levels and the ratio of RANKL/OPG in serum samples of breast cancer patients with AI-related MS-AEs with either the CC genotype or GG genotype of the RANKL promoter SNP rs7984870 (CC = 76 vs. GG = 32). C, D. Soluble OPG levels and the
Jingxuan Wang (435196), Shu Zhao (435198), Wenjie Ma (435202), Qijia Xuan (435204), Qingyuan Zhang (435205), Kangping Lu (435197), Dabei Tang (435201), Lei Liu (5074), Ying Song (352782), Hong Zhao (325)   +9 more
core   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source

Osteoprotegerin: Relationship to Breast Cancer Risk and Prognosis

Frontiers in Oncology, 2020
Osteoprotegerin (OPG) is a secreted member of the Tumor Necrosis Factor (TNF) receptor superfamily (TNFRSF11B), that was first characterized and named for its protective role in bone remodeling.
Dirk Geerts, Christina Chopra, Linda Connelly   +2 more
doaj   +1 more source

Osteoprotegerin levels in ST-elevation myocardial infarction: Temporal profile and association with myocardial injury and left ventricular function. [PDF]

PLoS ONE, 2017
BACKGROUND:Elevated levels of osteoprotegerin (OPG) have been associated with adverse outcomes in ST-elevation myocardial infarction (STEMI). However, the role of OPG in myocardial injury and adverse remodeling in STEMI patients remains unclear. The aims
Christian Shetelig, Shanmuganathan Limalanathan, Jan Eritsland, Pavel Hoffmann, Ingebjørg Seljeflot, Jon Michael Gran, Pål Aukrust, Thor Ueland, Geir Øystein Andersen   +8 more
doaj   +1 more source