Results 101 to 110 of about 648,698 (363)

Advanced Biomaterial Delivery of Hypoxia‐Conditioned Extracellular Vesicles (EVs) as a Therapeutic Platform for Traumatic Brain Injury

Advanced Science, EarlyView.
This research introduces a novel approach to enhance neuroregeneration following Traumatic Brain Injury (TBI). Extracellular Vesicles (EVs) are isolated from human neural progenitor cells under hypoxic conditions, leading to enhanced expression of neurogenic and angiogenic factors.
Joshua B. Stein, Songzi Zhang, Eun Ji Roh, Jeffrey Luo, Meizi Chen, Hyunjun Jang, Li Ling Goldston, Brandon Conklin, Inbo Han, Ki‐Bum Lee   +9 more
wiley   +1 more source

Housing, opportunities, motivation and engagement (HOME) for homeless youth at-risk for opioid use disorder: study protocol for a randomized controlled trial

Addiction Science & Clinical Practice, 2021
Background Homeless youth experience high rates of substance use disorders, exposures to violence, mental and physical health conditions, and mortality. They have been particularly affected by the opioid crisis.
Natasha Slesnick, Laura Chavez, Alicia Bunger, Ruri Famelia, Jodi Ford, Xin Feng, Sarah Higgins, Eugene Holowacz, Soren Jaderlund, Ellison Luthy, Allen Mallory, Jared Martin, Laura Walsh, Tansel Yilmazer, Kelly Kelleher   +14 more
doaj   +1 more source

Pregnancy- and parenting-related barriers to receiving medication for opioid use disorder: A multi-paneled qualitative study of women in treatment, women who terminated treatment, and the professionals who serve them

Women's Health
Background: Women face unique barriers when seeking treatment for substance use disorders, often related to pregnancy and parenting. Objectives: This study adds to the extant literature by elucidating the pregnancy- and parenting-related barriers women ...
Hannah B. Apsley, K. Brant, Sarah Brothers, Eric Harrison, Emma M. Skogseth, Robert P Schwartz, A. Jones   +6 more
semanticscholar   +1 more source

Trends in prior receipt of prescription opioid or adjuvant analgesics among patients with incident opioid use disorder or opioid-related overdose from 2006 to 2016

Drug and Alcohol Dependence, 2019
With increasing efforts to scrutinize and reduce opioid prescribing, limited data exist on the recent trend in receipt of prescription pain medications before diagnosis of opioid use disorder (OUD) or opioid-related overdose (OD).Using 2005-2016 Truven MarketScan Commercial Claims databases, we assessed trends in annual 1) incidence of OUD or OD and 2)
Yu-Jung Jenny Wei, Cheng Chen, Siegfried O. Schmidt, Wei-Hsuan LoCiganic, Almut G. Winterstein   +4 more
openaire   +3 more sources

Caenorhabditis elegans as a model system to identify therapeutics for alcohol use disorders [PDF]

, 2019
Alcohol use disorders (AUDs) cause serious problems in society and few effective treatments are available. Caenorhabditis elegans (C. elegans) is an excellent invertebrate model to study the neurobiological basis of human behavior with a conserved, fully
Bell, Richard L., Bredhold, Kristin E., Cheong, Mi C., Engleman, Eric A., Katner, Simon N., Neal-Beliveau, Bethany S., Steagall, Kevin B., III   +6 more
core   +1 more source

LncRNA THUMPD3‐AS1 Regulates Behavioral and Synaptic Structural Abnormalities in Schizophrenia via miR‐485‐5p and ARHGAP8

Advanced Science, EarlyView.
Schizophrenia (SCZ) is linked to synaptic structural deficits driven by dysregulated noncoding RNAs. Using the novel ceRNAxis pipeline, THUMPD3‐AS1/miR‐485‐5p/ARHGAP8 is identified as a key regulator of actin cytoskeletal remodeling through noncanonical RhoB/C‐ROCK2 signaling. Modulating this axis ameliorates SCZ‐like phenotypes in mice and aligns with
Xiaojuan Gong, Lingxi Chen, Xin Guo, Anna Jiang, Yayi He, Chunxia Yan, Liang Ma, Jiayang Gao, Jinyu Zhang, Bao Zhang   +9 more
wiley   +1 more source

“I never realized how hard recovery is.” A quasi‐experimental evaluation of a youth participatory action research project for opioid prevention

American Journal of Community Psychology, EarlyView.
Abstract Youth participatory action research (YPAR) has been effectively used for substance use prevention. Yet, YPAR has not been evaluated for opioids, which negatively impact individuals and communities across the United States. The current study evaluated an opioid‐focused YPAR project.
Elizabeth H. Weybright, Katherine Hampilos, Alison J. White, Cassandra Grinstead, Jennifer Fees, Melanie Greer, Erica L. Doering, Laurie M. Graham   +7 more
wiley   +1 more source

Hepatitis C care delivery practices among buprenorphine prescribers and non-prescribers: results from a survey of Washington state primary care providers

Addiction Science & Clinical Practice
Background Hepatitis C infection (HCV) and opioid use disorder (OUD) are syndemic in the U.S., thus primary care providers (PCPs) who treat OUD by prescribing buprenorphine can play key roles to advance HCV elimination targets.
Jocelyn R. James, Amelia M. Mohabir, Claire B. Simon, Allison Cole, Emalie Huriaux, Jon Stockton, Julien Rouvere, Judith I. Tsui   +7 more
doaj   +1 more source

Lead poisoning in opium abuser in Iran: A systematic review

International Journal of Preventive Medicine, 2018
Substance abuse and its consequences are major health hazards in the world. Opium addiction is a common form of substance abuse in Iran. Adulteration of illegal substances in the process of production and distribution of the drug in black market with ...
Kambiz Soltaninejad, Shahin Shadnia
doaj   +1 more source

Error-Related Activity in Striatal Local Field Potentials and Medial Frontal Cortex: Evidence From Patients With Severe Opioid Abuse Disorder [PDF]

, 2021
Elena Sildatke, Thomas Schüller, Theo O.J. Gründler, Markus Ullsperger, Veerle Visser‐Vandewalle, Daniel Huys, Jens Kuhn   +6 more
openalex   +1 more source