Results 81 to 90 of about 128,638 (328)

“I never realized how hard recovery is.” A quasi‐experimental evaluation of a youth participatory action research project for opioid prevention

American Journal of Community Psychology, EarlyView.
Abstract Youth participatory action research (YPAR) has been effectively used for substance use prevention. Yet, YPAR has not been evaluated for opioids, which negatively impact individuals and communities across the United States. The current study evaluated an opioid‐focused YPAR project.
Elizabeth H. Weybright, Katherine Hampilos, Alison J. White, Cassandra Grinstead, Jennifer Fees, Melanie Greer, Erica L. Doering, Laurie M. Graham   +7 more
wiley   +1 more source

Promoting Awareness of the Opioid Epidemic in Rural Vermont [PDF]

, 2017
Vermont is in the middle of an opioid epidemic. Heroin use fatalities are on the rise and the number of people in treatment for opioid use disorder in Rutland County has tripled in recent years.
Olson, Kathleen
core   +1 more source

A narrative review of trends and challenges of substance use in Punjab: a 10-year analysis of data from 2015 to 2024

Discover Public Health
Background Punjab, a northwestern state of India, is experiencing a serious substance use crisis with wide-ranging public health, social, and economic consequences.
Heena Sachdeva, Manish Sharma, Maninder
doaj   +1 more source

Housing, opportunities, motivation and engagement (HOME) for homeless youth at-risk for opioid use disorder: study protocol for a randomized controlled trial

Addiction Science & Clinical Practice, 2021
Background Homeless youth experience high rates of substance use disorders, exposures to violence, mental and physical health conditions, and mortality. They have been particularly affected by the opioid crisis.
Natasha Slesnick, Laura Chavez, Alicia Bunger, Ruri Famelia, Jodi Ford, Xin Feng, Sarah Higgins, Eugene Holowacz, Soren Jaderlund, Ellison Luthy, Allen Mallory, Jared Martin, Laura Walsh, Tansel Yilmazer, Kelly Kelleher   +14 more
doaj   +1 more source

The novel mu-opioid antagonist, GSK1521498, reduces ethanol consumption in C57BL/6J mice. [PDF]

, 2015
RATIONALE Using the drinking-in-the-dark (DID) model, we compared the effects of a novel mu-opioid receptor antagonist, GSK1521498, with naltrexone, a licensed treatment of alcohol dependence, on ethanol consumption in mice.
C Giuliano, C Giuliano, David N. Stephens, David R. Wille, DM Ignar, DN Stephens, DW Oslin, EA Rabiner, Edward T. Bullmore, EE Codd, F Kiefer, GH Jones, H Wit de, H Ziauddeen, HM Pettinati, JR Volpicelli, JS Rhodes, Kay Maltby, LA Berner, LA Parker, LD Middaugh, LS Hwa, Manolo Mugnaini, NK Kamdar, P Monti, PJ Nathan, PJ Nathan, Pradeep Nathan, S Loeber, Sam R. Miller, Sandra Sanchez-Roige, Tamzin L. Ripley, TJ Phillips, TL Ripley   +33 more
core   +1 more source

Designing an automated clinical decision support system to match clinical practice guidelines for opioid therapy for chronic pain [PDF]

, 2010
Background Opioid prescribing for chronic pain is common and controversial, but recommended clinical practices are followed inconsistently in many clinical settings.
AP Farmer, AX Garg, BM Kuehn, Brigit Vucic, Charles D Sintek, Dan Wang, David J Clark, Denise Daniels, DF Sittig, DL Hunt, DW Bates, G Worrall, J Gennari, Jack Rosenberg, Jan Elliott, JC Ballantyne, Jodie A Trafton, K Kawamoto, K Redmond, L Manchikanti, LM Frantsve, LM Yanni, M Glajchen, M Goldstein, Martha C Michel, Mary K Goldstein, MC Michel, Michael E Clark, MJ Pletcher, MK Goldstein, MK Goldstein, MK Goldstein, RA Miller, RN Shiffman, S Martins, Samson W Tu, SM Maviglia, SR Savage, Steve Balt, Susana B Martins, SW Tu, SW Tu, VA/DoD Opioid Therapy for Chronic Pain Working Group, W Dick, WM Tierney   +44 more
core   +3 more sources

Impact of different anesthetic protocols during anesthesia for the establishment of a porcine model of acute kidney injury

Animal Models and Experimental Medicine, EarlyView.
This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin, Mathieu Magnin, Axel Aigle, Timothée Schuhler, Jean‐Yves Ayoub, Romain Lac, Charlotte Slek, Thomas Brichart, Abdessalem Hammed, Vanessa Louzier   +9 more
wiley   +1 more source

Trends in prior receipt of prescription opioid or adjuvant analgesics among patients with incident opioid use disorder or opioid-related overdose from 2006 to 2016

Drug and Alcohol Dependence, 2019
With increasing efforts to scrutinize and reduce opioid prescribing, limited data exist on the recent trend in receipt of prescription pain medications before diagnosis of opioid use disorder (OUD) or opioid-related overdose (OD).Using 2005-2016 Truven MarketScan Commercial Claims databases, we assessed trends in annual 1) incidence of OUD or OD and 2)
Yu-Jung Jenny Wei, Cheng Chen, Siegfried O. Schmidt, Wei-Hsuan LoCiganic, Almut G. Winterstein   +4 more
openaire   +3 more sources

Lead poisoning in opium abuser in Iran: A systematic review

International Journal of Preventive Medicine, 2018
Substance abuse and its consequences are major health hazards in the world. Opium addiction is a common form of substance abuse in Iran. Adulteration of illegal substances in the process of production and distribution of the drug in black market with ...
Kambiz Soltaninejad, Shahin Shadnia
doaj   +1 more source

In vitro and in vivo pharmacological activities of 14-o-phenylpropyloxymorphone, a potent mixed mu/delta/kappa-opioid receptor agonist with reduced constipation in mice [PDF]

, 2018
Pain, particularly chronic pain, is still an unsolved medical condition. Central goals in pain control are to provide analgesia of adequate efficacy and to reduce complications associated with the currently available drugs.
Lattanzi, Roberta, Negri, Lucia, Rief, Silvia, Schmidhammer, Helmut, Spetea, Mariana.   +4 more
core   +2 more sources