Results 121 to 130 of about 593,453 (414)
Managing Prolonged Pain After Surgery: Examining the Role of Opioids. [PDF]
A notable minority of patients experience persistent postsurgical pain and some of these patients consequently have prolonged exposure to opioids. Risk factors for prolonged opioid use after surgery include preoperative opioid use, anxiety, substance ...
Pozek, John-Paul J.+2 more
core +1 more source
A Knowledge Graph-based Approach for Exploring the U.S. Opioid Epidemic [PDF]
The United States is in the midst of an opioid epidemic with recent estimates indicating that more than 130 people die every day due to drug overdose. The over-prescription and addiction to opioid painkillers, heroin, and synthetic opioids, has led to a public health crisis and created a huge social and economic burden.
arxiv
Neurogliaform and Ivy cells: a major class of nNOS expressing GABAergic neurons
Neurogliaform and Ivy cells are members of an abundant class of neuronal nitric oxide synthase (nNOS) expressing GABAergic interneurons found in diverse brain regions.
Caren eArmstrong+2 more
doaj +1 more source
A state-level study of opioid use disorder treatment access and neonatal abstinence syndrome [PDF]
Background Adult opioid use and neonatal abstinence syndrome (NAS) are growing public health problems in the United States (U.S.). Our objective was to determine how opioid use disorder treatment access impacts the relationship between adult opioid use ...
Abbinanti, Kassie+6 more
core +1 more source
Prescription Opioid Analgesics Commonly Unused After Surgery: A Systematic Review
Importance Prescription opioid analgesics play an important role in the treatment of postoperative pain; however, unused opioids may be diverted for nonmedical use and contribute to opioid-related injuries and deaths.
Mark C. Bicket+5 more
semanticscholar +1 more source
In this paper, I propose an economic theory that addresses the epidemic character of opioid epidemics. I consider a community in which individuals are heterogenous with respect to the experience of chronic pain and susceptibility to addiction and live through two periods.
openaire +4 more sources
A supramolecular gel platform based on poly(ethylene glycol) (PEG) is reported, offering injectability and degradability, with adjustable hydrophilic–hydrophobic ratios to produce RopC Gel for varying pain relief durations. RopC Gel enables sustained release of ropivacaine, induces pyroptosis in melanoma cells, and activates an immune response to ...
Jiangtao Lin+10 more
wiley +1 more source
Placenta ingestion by rats enhances d- and k-opioid antinociception, but suppresses m-opioid antinociception [PDF]
Ingestion of placenta or amniotic fluid produces a dramatic enhancement of centrally mediated opioid antinociception in the rat. The present experiments investigated the role of each opioid receptor type (m, d, k) in the antinociception-modulating ...
DiPirro, Jean M., Kristal, Dr. Mark B.
core
eDarkTrends: Harnessing Social Media Trends in Substance use disorders for Opioid Listings on Cryptomarket [PDF]
Opioid and substance misuse is rampant in the United States today, with the phenomenon known as the opioid crisis. The relationship between substance use and mental health has been extensively studied, with one possible relationship being substance misuse causes poor mental health.
arxiv
* Abbreviation: POU — : persistent opioid use The opioid crisis is currently front-page news.1 The United States leads the world in per capita opioid use as global consumption steadily increases.2,3 The percentage of deaths from opioids, fentanyl, and heroin is rising year after year.3 Harbaugh et al4 used a commercial claims database ...
openaire +3 more sources