Results 61 to 70 of about 659,970 (390)

Cannabis combined with oxycodone for pain relief in fibromyalgia pain: a randomized clinical self-titration trial with focus on adverse events

Frontiers in Pain Research
ObjectivesWe determined whether adding cannabis to oxycodone for chronic non-cancer pain management could reduce treatment-related adverse effects (AEs) while maintaining effective analgesia.MethodsIn this open-label study, fibromyalgia patients aged ≥18 
Cornelis Jan van Dam, Cornelis Jan van Dam, Cornelis Kramers, Cornelis Kramers, Cornelis Kramers, Arnt Schellekens, Arnt Schellekens, Arnt Schellekens, Arnt Schellekens, Marcel Bouvy, Marcel Bouvy, Eveline van Dorp, Eveline van Dorp, Mikael A. Kowal, Erik Olofsen, Albert Dahan, Albert Dahan, Albert Dahan, Albert Dahan, Marieke Niesters, Marieke Niesters, Marieke Niesters, Monique van Velzen, Monique van Velzen   +23 more
doaj   +1 more source

Opioid use disorder patients’ perceptions of healthcare delivery platforms

SAGE Open Medicine, 2016
Objectives: To assess the acceptability and quality of web-based videoconferencing telemedicine consultation platform in the treatment of opioid use disorder at TrueNorth Medical Centre.
Uros Rakita, Peter Giacobbe, Chris Cavacuiti   +2 more
doaj   +1 more source

Ultrasound-guided trigeminal nerve block and its comparison with conventional analgesics in patients undergoing faciomaxillary surgery: Randomised control trial

Indian Journal of Anaesthesia, 2018
Background and Aims: Ultrasound (USG)-guided injection in pterygopalatine fossa is an indirect approach to block the trigeminal nerve. Trigeminal nerve block for maxillofacial surgeries may provide preemptive analgesia, reduce opioid consumption and ...
Amarjeet Kumar, Chandni Sinha, Ajeet Kumar, Poonam Kumari, Sailesh Kumar Mukul   +4 more
doaj   +1 more source

Early life nociceptive stimulus and fentanyl exposure increase hippocampal neurogenesis and anxiety but do not affect spatial learning and memory

Frontiers in Neuroscience, 2022
This study aimed to determine whether preemptive fentanyl administration in neonatal rats reduces the impact of a nociceptive stimulus initiated during the first day of life (P1) on hippocampal neurogenesis, behavior, and learning. At P1, Wistar rat pups
Debora da Silva Bandeira Rêgo, Clivandir S. Silva, Luiz Eugenio A. M. Mello, Luiz Eugenio A. M. Mello, Ana Teresa Figueiredo Stochero Leslie, Ana Teresa Figueiredo Stochero Leslie   +5 more
doaj   +1 more source

The Opioid-Tolerant Patient: Opioid Optimization [PDF]

The Journal of Arthroplasty, 2020
Chronic opioid use and abuse continue to plague our country despite efforts to curtail their use. Patients on chronic opioids (opioids tolerant) who undergo total joint arthroplasty have been clearly shown to have higher rates of complications, infection, and early revision compared to the opioid-naïve patients.
Amanda Nelli, Padma Gulur
openaire   +3 more sources

The Burden of Opioid-Related Mortality in the United States

JAMA Network Open, 2018
Key Points Question What has been the burden of opioid-related deaths in the United States over a recent 15-year period? Findings In this serial cross-sectional study, we found that the percentage of all deaths attributable to opioids increased 292 ...
T. Gomes, Mina Tadrous, M. Mamdani, J. Paterson, D. Juurlink   +4 more
semanticscholar   +1 more source

State-Level Economic Costs of Opioid Use Disorder and Fatal Opioid Overdose — United States, 2017

MMWR. Morbidity and mortality weekly report, 2021
Approximately 47,000 persons in the United States died from an opioid-involved overdose in 2018 (1), and 2.0 million persons met the diagnostic criteria for an opioid use disorder in 2017 (2). The economic cost of the U.S.
Feijun Luo, Mengyao Li, C. Florence
semanticscholar   +1 more source

Sleep Matters: Exploring the Link Between Sleep Disturbances and Fatigue in Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Fatigue is a prevalent and debilitating symptom for patients with rheumatoid arthritis (RA). Although patients and rheumatologists often attribute fatigue to inflammation, other factors such as sleep disturbances are frequently overlooked. This study aims to explore the relationship between subjective (self‐reported) and objective (actigraphy
Natalia V. Chalupczak, Burcu Aydemir, Ariel Isaacs, Lutfiyya N. Muhammad, Jing Song, Kathryn J. Reid, Daniela Grimaldi, Mary Carns, Kathleen Dennis‐Aren, Dorothy D. Dunlop, Beth I. Wallace, Phyllis C. Zee, Yvonne C. Lee   +12 more
wiley   +1 more source

The genomics of neonatal abstinence syndrome [PDF]

, 2017
Significant variability has been observed in the development and severity of neonatal abstinence syndrome (NAS) among neonates exposed to prenatal opioids.
Cole, F. Sessions, Davis, Jonathan M, Wegner, Daniel J   +2 more
core   +3 more sources

Postsurgical prescriptions for opioid naive patients and association with overdose and misuse: retrospective cohort study

British medical journal, 2018
Objective To quantify the effects of varying opioid prescribing patterns after surgery on dependence, overdose, or abuse in an opioid naive population. Design Retrospective cohort study.
G. Brat, D. Agniel, A. Beam, Brian K. Yorkgitis, Mark C. Bicket, Mark L. Homer, Kathe P. Fox, Daniel B Knecht, C. McMahill-Walraven, N. Palmer, I. Kohane   +10 more
semanticscholar   +1 more source