Results 111 to 120 of about 38,144 (289)

Should I Stay or Should I Go? A Qualitative Exploration of Stigma and Other Factors Influencing Opioid Agonist Treatment Journeys [PDF]

, 2023
Victoria R. Carlisle, Olivia Maynard, Darren Bagnall, Matthew Hickman, Jon Shorrock, Kyla H Thomas, Joanna Kesten   +6 more
openalex   +1 more source

Peri‐operative pain management in major lower extremity amputation in vascular Surgery: a UK anaesthetic and vascular surgery Delphi consensus study*

Anaesthesia, EarlyView.
Summary Introduction Major lower extremity amputations occurring secondary to vascular disease remain prevalent worldwide. Pain surrounding these procedures is complex, multifactorial and associated with poor functional and psychosocial outcomes. The evidence base informing pain management approaches in major lower extremity amputations remain largely ...
Thanapon Ekkunagul, Caitlin Sara MacLeod, Anna Celnik, John Chalmers, Ross Thomson, Alan J. R. Macfarlane, David Bosanquet, John Nagy, Patrice Forget, the Delphi expert panel, Abhijoy Chakladar, Ahmed Abidia, Alan Fayaz, Alan Macfarlane, Alasdair Taylor, Alastair Thomson, Alexander Bell, Amy Sadler, Andrea Harvey, Andrew Mitchell, Andrew Tambyraja, Andrew William Garnham, Andrey Varvinskiy, Ankur Thapar, Anna Celnik, Caroline Curry, Catherine Western, Catriona Semple, Christopher G Davies, Craig Forrest, David Bosanquet, Denis Harkin, Diane Rosemary Hildebrand, Douglas James MacKenzie, Emma Elizabeth Florence Scott, Emma Jannine Baird, Ferdinand Serracino‐Inglott, Fiona Myint, Frances Kent, Francesco Torella, Gareth Harrison, George A. Antoniou, George Edward Smith, Graeme A McLeod, Ian Chetter, Indran Raju, John Chalmers, John Nagy, John O'Donoghue, Jonathan Paul Seeley, Kaji Sritharan, Keith Hussey, Keith Jones, Kersten Morgan Bates, Kevin Graham Mercer, Kieran Murphy, Lisa Anne Grimes, Matt Metcalfe, Maureen Sweeney, Michael McCusker, Michael Neil, Michelle Lamont, Mohamed Elsherif, Nat Haslam, Naveeta Maini, Nicholas Stuart Greaves, Patrick Coughlin, Patrice Forget, Peter Merjavy, Robert Hinchliffe, Rob Sayers, Ross Thomson, Russell William Jamieson, Sachin R Kulkarni, Sandeep Bahia, Sandip Nandhra, Serena Goon, Tanim Siddiqui, Tim Stansfield, Vanessa Fludder, Vikas Kaura, Vishal Gupta   +81 more
wiley   +1 more source

Comparative Safety Analysis of Opioid Agonist Treatment in Pregnant Women with Opioid Use Disorder: A Population-Based Study [PDF]

, 2023
Shuang Wang, Kimford J. Meador, Jayne Pawasauskas, Adam K. Lewkowitz, Kristina E. Ward, Todd Brothers, Abraham G. Hartzema, Brian J. Quilliam, Xuerong Wen   +8 more
openalex   +1 more source

Survey describing the perspectives and practices of Australian veterinarians to pain management in horses

Australian Veterinary Journal, EarlyView.
Objective To describe Australian practices and attitudes regarding equine analgesia. Study Design Cross‐sectional anonymous, voluntary survey of Australian veterinarians treating equine patients. Methods Australian veterinarians in equine or mixed practices completed a six‐section, 60‐question survey between November 2019 to August 2020.
A Whitelock, W Goodwin, L Dryburgh, PP Mshelbwala, L Rae, L Marwedel, T Lok, K Kemp, AJ Stewart   +8 more
wiley   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

Interim opioid agonist treatment for opioid addiction

Opioid use disorder is a public health problem and treatment variability, coverage and accessibility poses some challenges. The study's objective is to review the impact of interim opioid agonist treatment (OAT), a short-term approach for patients awaiting standard OAT, in terms of treatment retention, access to standard OAT, quality of life and ...
Samsó Jofra, Laura||, Puig Reixach, Maria Teresa||, Solà, Ivan||, Trujols, Joan||   +3 more
openaire   +1 more source

Psilocybin as a novel treatment for chronic pain

British Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey, Reena Lasrado, Maria Maiarú, Gary J. Stephens   +3 more
wiley   +1 more source

Evidence that 5‐HT2A receptor signalling efficacy and not biased agonism differentiates serotonergic psychedelic from non‐psychedelic drugs

British Journal of Pharmacology, EarlyView.
Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito, Sridhar Vasudevan, Shaun Hurley, Gary Gilmour, Frederick Westhorpe, Grant Churchill, Trevor Sharp   +6 more
wiley   +1 more source

Uptake and predictors of direct-acting antiviral treatment for hepatitis C among people receiving opioid agonist therapy in Sweden and Norway: a drug utilization study from 2014 to 2017 [PDF]

, 2020
Christer Frode, Jørn Henrik Vold, Svetlana Skurtveit, Ingvild Odsbu, Fatemeh Chalabianloo, Aaron G. Lim, Kjell Arne Johansson, Lars Thore Fadnes   +7 more
openalex   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source