Results 91 to 100 of about 8,834,434 (252)
BMC Infectious Diseases, 2018 Background People who inject drugs (PWID) constitute 60% of the approximately 5 million people in the U.S. infected with hepatitis C virus (HCV). Treatment of PWID is complex due to addiction, mental illness, poverty, homelessness, lack of positive ...
Matthew J. Akiyama +7 more
doaj +1 more source
Phytotherapy Research, EarlyView.ABSTRACT N‐acylethanolamines (NAEs) are endogenous fatty acid amides structurally related to the endocannabinoid anandamide and function as bioactive lipid mediators with broad regulatory roles in inflammation and neuroinflammation. Among pattern‐recognition receptors, Toll‐like receptor 4 (TLR4) occupies a central position in innate immune ...
Damiana Scuteri +5 more
wiley +1 more source
Butorphanol: Effects of a Prototypical Agonist-Antagonist Analgesic on κ-Opioid Receptors
Journal of Pharmacological Sciences, 2005 The opioid analgesic, butorphanol (17-cyclobutylmethyl-3,14-dihydroxymorphinan) tartrate is a prototypical agonist-antagonist opioid analgesic agent whose potential for abuse has been the cause of litigation in the United States.
Stephen Commiskey +3 more
doaj +1 more source
Government as orchestrator: Ecosystem transformation at scale and speed
Strategic Management Journal, EarlyView.Abstract Research Summary Grand challenges are ecosystem challenges: success depends on aligning a multilateral set of public and private sector actors whose interdependent contributions determine whether a mission is achieved. This study examines how government can orchestrate ecosystem alignment by leveraging distinctive capabilities to deliver ...
Ron Adner
wiley +1 more source
Substance Abuse Treatment, Prevention, and PolicyBackground Physical or mental health comorbidities are common among people with substance use disorders undergoing opioid agonist therapy. As both a preventive and treatment strategy, exercise offers various health benefits for several conditions ...
Einar Furulund +5 more
doaj +1 more source
Indian Journal of PsychiatryPerinatal opioid use is the major public health concern worldwide due to its hazardous effect on the mother and the developing fetus. Opioid agonist maintenance treatment with buprenorphine or methadone has been the recommended treatment for opioid ...
Piyali Mandal +3 more
doaj +1 more source
Opioid Dependence Treatment: Options In Pharmacotherapy [PDF]
, 2009 The development of effective treatments for opioid dependence is of great importance given the devastating consequences of the disease. Pharmacotherapies for opioid addiction include opioid agonists, partial agonists, opioid antagonists, and alpha-2 ...
Dodrill, Carrie L +2 more
core +1 more source
The Milbank Quarterly, EarlyView.Policy Points Position Universal, High‐Quality Education as a Foundational Public Health Strategy. Long‐term health and life expectancy in the United States are shaped more by educational attainment than by any other single factor. Disparities in access to early childhood, K‐12, and higher education perpetuate cycles of chronic disease, economic ...
ALI H. MOKDAD +2 more
wiley +1 more source
Opioid Use Disorder: Economic Burden and Treatment Barriers in Australia
, 2023 This research explored the economic costs of heroin dependence and identified the barriers to accessing opioid agonist treatments for those with opioid use disorders.
Natasha Hall (11570614)
core
Protodesnitazene: The identification and tissue distribution of a new nitazene
Journal of Forensic Sciences, EarlyView.Abstract Multiple new analogues from the 2‐benzyl benzimidazole or “nitazene” class of drugs have emerged on the drug market in recent years. Nitazenes are highly potent μ‐opioid receptor agonists that present a substantial public health concern due to their elevated risk of severe toxicity in overdose and their significant potential for misuse.
Andrew Griffiths +4 more
wiley +1 more source