Results 111 to 120 of about 292,142 (337)

Rapid transitional response to the COVID-19 pandemic by opioid agonist treatment programs in Ukraine

Journal of Substance Abuse Treatment, 2020
On March 16, 2020, Ukraine's Ministry of Health issued nonspecific interim guidance to continue enrolling patients in opioid agonist therapies (OAT) and transition existing patients to take-home dosing to reduce community COVID-19 transmission.
A. Meteliuk, Samy J Galvez de Leon, Lynn M. Madden, I. Pykalo, T. Fomenko, Myroslava Filippovych, Scott O. Farnum, Sergii Dvoryak, Z. Islam, F. Altice   +9 more
semanticscholar   +1 more source

Things We Do for No Reason™: Withholding opioids among patients with acute pain and opioid use disorder

Journal of Hospital Medicine, EarlyView.
Abstract Hospitalists care for patients with acute pain who have an opioid use disorder and require pain management. Hospitalists may withhold opioids for acute pain due to a variety of reasons. However, adequate pain management in patients with opioid use disorder, including with opioids, is the standard of care. This piece explains how to best manage
Anna‐Maria South, Susan L. Calcaterra, Marlene Martin   +2 more
wiley   +1 more source

Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor. [PDF]

, 2018
The intrinsic efficacy of orthosteric ligands acting at G-protein-coupled receptors (GPCRs) reflects their ability to stabilize active receptor states (R*) and is a major determinant of their physiological effects.
Livingston, Kathryn E, Mahoney, Jacob P, Manglik, Aashish, Sunahara, Roger K, Traynor, John R   +4 more
core  

Evidence of increased Fentanyl use during the COVID-19 pandemic among opioid agonist treatment patients in Ontario, Canada

The International journal on drug policy, 2020
Background Amid the opioid crisis, the health care system is restructuring to prevent and treat COVID-19. Individuals in opioid agonist treatment (OAT) are uniquely challenged because of disruption to treatment, medication diversion, and isolation during
K. Morin, Shreedhar Acharya, J. Eibl, D. Marsh   +3 more
semanticscholar   +1 more source

Hell's Itch: A Self‐Case Report

JEADV Clinical Practice, EarlyView.
ABSTRACT Hell's itch is a severely distressing dermatological condition characterized by the onset of incessant itching and intolerable pain 2–3 days post‐sunburn. It is underdiagnosed and underreported, and no definitive management framework has yet been developed.
Kai Peter Moors, Willem I. Visser
wiley   +1 more source

The opioid crisis: past, present and future policy climate in Ontario, Canada

Substance Abuse Treatment, Prevention, and Policy, 2017
Background Addressing opioid use disorder has become a priority in Ontario, Canada, because of its high economic, social and health burden. There continues to be stigma and criticism relating to opioid use disorder and treatment options.
Kristen A. Morin, Joseph K. Eibl, Alexandra M. Franklyn, David C. Marsh   +3 more
doaj   +1 more source

Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]

, 1995
Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core   +1 more source

A national model of remote care for assessing and providing opioid agonist treatment during the COVID-19 pandemic: a report

Harm Reduction Journal, 2020
Background Health services globally are struggling to manage the impact of COVID-19. The existing global disease burden related to opioid use is significant.
D. Crowley, Íde Delargy
semanticscholar   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Use of microdoses for induction of buprenorphine treatment with overlapping full opioid agonist use: the “Bernese method”

Substance Abuse and Rehabilitation, 2016
Robert Hämmig,1 Antje Kemter,2 Johannes Strasser,2 Ulrich von Bardeleben,1 Barbara Gugger,1 Marc Walter,2 Kenneth M Dürsteler,2 Marc Vogel2 1Division of Addiction, University Psychiatric Services Bern, Bern, Switzerland; 2Division of Substance ...
Hämmig R, Kemter A, Strasser J, von Bardeleben U, Gugger B, Walter M, Dürsteler KM, Vogel M   +7 more
doaj