Results 101 to 110 of about 38,893 (219)

Glucagon‐Like Peptide‐1 Receptor Agonists and Incident Major Adverse Liver Outcomes in People With Type 2 Diabetes and Metabolic Dysfunction‐Associated Steatotic Liver Disease

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Treatment options for metabolic dysfunction‐associated steatotic liver disease (MASLD) are limited. While glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) and sodium‐glucose cotransporter‐2 (SGLT‐2) inhibitors improve cardiovascular outcomes, comparative effectiveness on liver‐related outcomes remains unclear.
Gregor A. Maier, Ramon A. Hofmann, Michael Roden, Wolfgang Rathmann, Oliver Kuss   +4 more
wiley   +1 more source

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

Rhinoscopy in horses: Endoscopic anatomy, technique and equipment

Equine Veterinary Education, EarlyView.
Summary Rhinoscopy is a valuable imaging modality for diagnosis of conditions affecting the nasal and paranasal cavities in horses. Despite wide application in clinical practice, systematic endoscopic evaluation of the conchal bullae, nasal conchae and adjacent structures has seldom been described.
J. W. C. Lopes, R. P. Mendes, S. L. Paredes, K. A. G. Vallejo, P. S. Rocha, R. G. S. Dória, R. R. Corrêa   +6 more
wiley   +1 more source

Spatiotemporal dynamics of β‐arrestin‐mediated Src activation in 5‐HT7 receptor signaling pathway

The FEBS Journal, EarlyView.
GPCRs induce distinct cellular responses via G protein‐ or β‐arrestin‐mediated signaling pathways. This study revealed that β‐arrestin‐biased 5‐HT7R ligand induces slow, sustained Src activation, contrasting with transient G protein‐mediated activation.
Hyunbin Kim, Yong Woo Lee, Huimin Lee, Eunseo Park, Jieon Lee, Hae Nim Lee, Kyeong‐Man Kim, Hyunah Choo, Jihye Seong   +8 more
wiley   +1 more source

Retention in opioid agonist treatment during pregnancy and variations according to treatment and maternal characteristics. [PDF]

Addiction
Varney B, Jones N, Bharat C, Brett J, Degenhardt L, Oei JL, Pearson SA, Havard A, Tran DT.   +8 more
europepmc   +1 more source

Suzetrigine as a novel treatment for headache disorders: A case series

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Suzetrigine is a selective voltage‐gated sodium channel blocker that was recently approved by the US Food and Drug Administration for the treatment of acute pain. We retrospectively evaluated the efficacy and tolerability of suzetrigine for the treatment of different headache disorders in patients refractory to standard treatments in an ...
Molly Fensterwald, Jordan Johnson, Angel Moreno, Shawn Conger‐Love, Charles Flippen, Chelsea Hesterman, Mollie Johnston, Joshua Kamins, Karla Minota, Peony Pak, Salman Hashim, Thanh‐Liem Huynh‐Tran, Noelle Kobayashi, Bradley Shane, Andrew Charles, Sinifunanya Nwaobi   +15 more
wiley   +1 more source

An opioid-withholding human laboratory paradigm during opioid agonist treatment for opioid use disorder and chronic pain: Phase- and dose-dependent effects of cannabidiol. [PDF]

Neuropsychopharmacology
P A Costa G, Sofuoglu M, Compton P, Ranganathan M, Pittman B, De Aquino JP.   +5 more
europepmc   +1 more source

Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis

International Journal of Dermatology, EarlyView.
Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller, Helmut Beltraminelli, Wolf‐Henning Boehncke, Maximilian Böhm, Antonio Cozzio, Peter Häusermann, Ahmad Jalili, Antonios G. A. Kolios, Claudia Lang, Eva Loos, Christoph Schlapbach, Curdin Conrad   +11 more
wiley   +1 more source

Postpartum retention in opioid agonist treatment for opioid dependence: A population-based cohort study. [PDF]

Arch Womens Ment Health
Zhou J, Varney B, Jones N, Bharat C, Degenhardt L, Havard A, Tran DT.   +6 more
europepmc   +1 more source

The Influence of Oral Health Related Knowledge, Attitudes and Practices on Oral Health Risk‐Related Behaviours of People in Custodial Settings: An Integrative Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To explore the influence of oral health‐related knowledge, attitudes and practices on oral health risk‐related behaviours of people in custodial settings. Design Integrative review. Data Sources Scopus, ProQuest Central, Web of Science, Medline, CINAHL, Academic Search Complete, PsycINFO and Education Research Complete were searched in ...
Izabella Barak, Brandon W. Smith, Ajesh George, Rebecca Bosworth, Della Maneze, Kate Inderwisch, Yenna Salamonson   +6 more
wiley   +1 more source