Results 51 to 60 of about 410,228 (317)
SAGE Open Medicine, 2019 Objectives: Pain is considered the most common and debilitating symptom reported by patients affected by cancer, and opioids are at the front line for its effective management.
A. Charalambous +3 more
semanticscholar +1 more source
TREATMENT OF PAIN IN PEDIATRIC PATIENTS [PDF]
Journal of IMAB, 2016 The article clarifies that pain is a multidimensional phenomenon both in adults and children. The authors reviewed the literature and surveyed the clinical data on the management of pain in pediatric patients. The conclusion was made that pain management
Nikolay Yanev, Mila Vlaskovska
doaj +1 more source
Tapentadol extended release for the management of chronic neck pain [PDF]
, 2017 BACKGROUND: The role of opioids in the management of chronic neck pain is still poorly investigated. No data are available on tapentadol extended release (ER).
Coluzzi, Flaminia
core +1 more source
PLoS ONE, 2019 PurposeTo estimate the prevalence of use of analgesics in Brazil; and to characterize this use, according to sociodemographic and health-related characteristics.MethodsA cross-sectional population-based study (National Survey on Access, Use and Promotion
Tatiane da Silva Dal Pizzol +5 more
doaj +1 more source
JAMA Internal Medicine, 2016 IMPORTANCE Opioid analgesics are commonly used for low back pain, however, to our knowledge there has been no systematic evaluation of the effect of opioid dose and use of enrichment study design on estimates of treatment effect.
Christina Abdel Shaheed +4 more
semanticscholar +1 more source
Administration of Tramadol or Buprenorphine via the drinking water for post-operative analgesia in a mouse-osteotomy model [PDF]
, 2019 Adequate analgesia is essential whenever pain might occur in animal experiments. Unfortunately, the selection of suitable analgesics for mice in bone-linked models is limited. Here, we evaluated two analgesics - Tramadol [0.1 mg/ml (Tlow) vs.
Buttgereit, Frank +7 more
core +1 more source
Binding Pathway of Opiates to $μ$ Opioid Receptors Revealed by Unsupervised Machine Learning [PDF]
, 2018 Many important analgesics relieve pain by binding to the $\mu$-Opioid Receptor ($\mu$OR), which makes the $\mu$OR among the most clinically relevant proteins of the G Protein Coupled Receptor (GPCR) family. Despite previous studies on the activation pathways of the GPCRs, the mechanism of opiate binding and the selectivity of $\mu$OR are largely ...
arxiv +1 more source
A Prospective Randomized Study Analyzing Preoperative Opioid Counseling in Pain Management After Carpal Tunnel Release Surgery. [PDF]
, 2017 PURPOSE: Prescription opioid misuse has become increasingly prevalent in the United States. Preoperative opioid counseling has been proposed to decrease opioid consumption after surgery.
Alter, Todd H., Ilyas, Asif M
core +3 more sources
Nature Communications, 2019 Tolerance and other side effects are important limitations to the use of opioids as analgesics. In this study, the authors generated mice lacking phosphorylation sites on the µ-opioid receptor to assess their contribution to the analgesic, tolerance and ...
A. Kliewer +8 more
doaj +1 more source
Use of Opioid Analgesics Before and After Gastric Bypass Surgery in Sweden: a Population-Based Study
Obesity Surgery, 2018 BackgroundLittle is known regarding the use of opioid analgesics among patients who have undergone bariatric surgery.The Roux-en-Y gastric bypass (RYGB) procedure has been shown to significantly increase the rate of absorption of and exposure to morphine,
Stefan Wallén +3 more
semanticscholar +1 more source