Results 91 to 100 of about 52,732 (301)
Pain Research and Management, 2000 It has been suggested that opioid tolerance and dependence share common mechanisms with neuropathic pain. This short review deals with the role of glutamate and glutamate receptors in opioid tolerance and dependence, and neuropathic pain.
Marian E Fundytus
doaj +1 more source
Opioid dependence and management
, 2009 Illicit opioid use, typically involving the use of heroin, is a significant health problem internationally. In many developed countries, dependent heroin users are typically daily, or near daily, injectors of heroin, and of other opioid and sedative ...
Mattick, Richard P. +2 more
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, 2010 The current standard for clinical treatment of dependence on heroin and other opioids is to maintain the dependence with slower-acting opioids like methadone or buprenorphine.
Kunøe, Nikolaj
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Precision medicine in paediatrics: Progress and priorities
British Journal of Clinical Pharmacology, EarlyView.Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain +3 more
wiley +1 more source
Stress-evoked opioid release inhibits pain in major depressive disorder
, 2008 To determine whether stress-evoked release of endogenous opioids might account for hypoalgesia in major depressive disorder (MDD), the μ-opioid antagonist naltrexone (50 mg) or placebo was administered double-blind to 24 participants with MDD and to 31 ...
Frew, A.K., Drummond, P.D.
core
, 2018 Background: Dependence upon one substance may increase vulnerability for dependence on other substances. This study aimed to i) examine the association between opioid dependence and alcohol use and dependence; and ii) identify demographic, mental health,
Briony Larance +13 more
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Exploring new avenues: Psychedelic‐assisted therapy for young people
British Journal of Clinical Pharmacology, EarlyView.Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou +3 more
wiley +1 more source
Hepatitis Infection in the Treatment of Opioid Dependence and Abuse
, 2008 Many new and existing cases of viral hepatitis infections are related to injection drug use. Transmission of these infections can result directly from the use of injection equipment that is contaminated with blood containing the hepatitis B or C virus or
Kenneth Hoffman +6 more
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Codeine toxicity via breast Milk: Can this occur and implications for opiate therapy in children
British Journal of Clinical Pharmacology, EarlyView.Codeine is commonly used in combination analgesic products. The use of codeine during breastfeeding can rarely be associated with serious adverse effects related to genetic polymorphisms affecting codeine's metabolism and disposition. Clinicians treating infants of breastfeeding mothers should be aware of this rare but potentially serious complication.
Michael Rieder
wiley +1 more source
Why do we need to control alcohol use through legislative measures? A south east asia perspective?
Indian Journal of Community Medicine, 2010 Background: Even though prevalence of alcohol use in the world is very high, it has not been brought under legal control in several countries, contrary to other controlled substances like opium, cocaine, cannabis, and so on.
Saddichha Sahoo +2 more
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