Results 91 to 100 of about 1,267,582 (207)
Opioid dependence and management
, 2009 Illicit opioid use, typically involving the use of heroin, is a significant health problem internationally. In many developed countries, dependent heroin users are typically daily, or near daily, injectors of heroin, and of other opioid and sedative ...
Mattick, Richard P. +2 more
core
Prenatal exposure to buprenorphine or methadone: effects on physical growth, neurological development and temperament in early childhood. [PDF]
, 2012 Pharmaceutical maintenance with methadone is the current gold standard for pregnant women with opioid-dependence. While there are many benefits of methadone, its use during pregnancy is associated with high rates of neonatal abstinence syndrome, and long
Whitham, Justine N.
core
Benzodiazepines use in primary care England: Prescribing patterns and adverse consequences
British Journal of Clinical Pharmacology, EarlyView.Aims Benzodiazepines (BZDs) are commonly prescribed for anxiety and insomnia but carry risks such as dependence, adverse drug reactions (ADRs) and mortality. Despite deprescribing efforts, the influence of recent prescribing trends, COVID‐19 and adverse outcomes on prescribing patterns in England remains uncertain.
Alvina Chaudhry +3 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Rocavorexant (INDV‐2000), a selective orexin‐1 receptor antagonist, reduces drug self‐administration and anxiety in nonclinical studies. This Phase 1 programme evaluated the safety, pharmacokinetics and pharmacodynamics of rocavorexant in healthy volunteers and treatment‐seeking individuals with opioid use disorder (OUD).
Martin Kankam +5 more
wiley +1 more source
Compulsivity in opioid dependence [PDF]
, 2018 Objective: This study aimed to investigate the relationship between compulsivity versus impulsivity and structural MRI abnormalities in opioid dependence.Method: We recruited 146 participants: i) patients with a history of opioid dependence due to ...
Serenella Tolomeo +9 more
core +1 more source
BMEMat, EarlyView.A glycosylated dendrimer nanoamplifier hijacks DNA damage‐immune crosstalk for enhanced radio‐immunotherapy of glioblastoma. The responsive release of demethylcantharidin simultaneously blocks repair‐mediated resistance by inhibiting DNA repair and overcomes adaptive immune resistance.
Cong Song +10 more
wiley +1 more source
Social trauma and the mu-opioid system in depression [PDF]
, 2011 The overarching thesis under investigation is that the endogenous opioid system plays a key role in depression subsequent to traumatic childhood social experiences. This is suggested by the fact that animal work indicates that mu-opioids robustly mediate
Malcolm-Smith, Susan
core +1 more source
JA Clinical Reports, 2019 Background Long-term opioid treatment for chronic non-cancer pain has become controversial, given the increasing prevalence of opioid dependence. However, there is little information on therapeutic strategies for this condition in Japanese patients. Here,
Marie Shigematsu-Locatelli +8 more
doaj +1 more source
Antimicrobial Peptides and Peptidomimetics in Foods – A Synthetic Foray
ChemFoodChem, EarlyView.This Review discusses AMPs in foods and their syntheses. It espouses facile methods to make them accessible and suggests their utility in the mitigation and eradication of the burgeoning maladies of antimicrobial and multidrug resistance (AMR and MDR).
Josephat U. Izunobi +2 more
wiley +1 more source
Pregabalin use in HIV-infected patients with opioid dependence syndrome
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2018 Te purpose of the current study was to identify an abuse potential of pregabalin in HIVinfected patients with opioid use disorder long time using pregabaline. A cross-sectional study was performed at the St.
M. Ya. Kissin +4 more
doaj +1 more source