Results 61 to 70 of about 1,267,582 (207)

Iatrogenic physiologic opioid dependence masquerading as recurrent acute pancreatitis flares: case series

Addiction Science & Clinical Practice
Patients with recurrent acute flares of pancreatitis—especially those receiving frequent opioid treatment for pain—can develop physiologic dependence to opioids.
David Dayan-Rosenman, Sara Diletti-Swenson, Nisha Ghayalod, Randi Sokol   +3 more
doaj   +1 more source

Long-Acting Injectable naltrexone for the Management of patients with Opioid Dependence

Substance Abuse: Research and Treatment, 2011
Opioid dependence is a condition with serious clinical ramifications. Treatment has focused on detoxification, agonist therapy with methadone or buprenorphine, or remission maintenance with the opioid antagonist, naltrexone.
Kimberly L. Kjome, F. Gerard Moeller
doaj   +1 more source

Possible Involvement of Endogenous Opioid System Located Downstream of α7 Nicotinic Acetylcholine Receptor in Mice With Physical Dependence on Nicotine

Journal of Pharmacological Sciences, 2014
.: We previously reported that nicotine (NIC)-induced analgesia was elicited in part by activation of the endogenous opioid system. Moreover, it is well known that NIC has physical-dependence liability, but its mechanism is unclear.
Keiko Ueno, Norikazu Kiguchi, Yuka Kobayashi, Fumihiro Saika, Naoki Wakida, Chizuko Yamamoto, Takehiko Maeda, Masanobu Ozaki, Shiroh Kishioka   +8 more
doaj   +1 more source

Age‐Related Lamin B1 Deficiency Activates SLC7A11‐Dependent Disulfidptosis to Impair Osteogenesis via Intercepting Mitochondrial Fission

Advanced Science, EarlyView.
This study reveals that age‐related LMNB1 deficiency in mesenchymal stem cells epigenetically upregulates SLC7A11, triggering actin disulfidptosis and mitochondrial dysfunction. This cascade impairs bone formation in senile osteoporosis. Furthermore, researchers identified the FDA‐approved drug naldemedine as a targeted SLC7A11 inhibitor to reverse ...
Wenhui Yu, Qibo Li, Weihao Zhang, Guan Zheng, Junhua Chen, Yipeng Zeng, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Jiajie Lin, Zepeng Su, Zhongyu Xie   +12 more
wiley   +1 more source

Health disparities in chronic liver disease

Hepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew   +3 more
wiley   +1 more source

Buprenorphine maintenance treatment and its outcome among opioid dependent pregnant women: A case series from India

Indian Journal of Psychiatry
Perinatal opioid use is the major public health concern worldwide due to its hazardous effect on the mother and the developing fetus. Opioid agonist maintenance treatment with buprenorphine or methadone has been the recommended treatment for opioid ...
Piyali Mandal, Rajkumar Sanahan, Yesh Chandra Singh, Atul Ambekar   +3 more
doaj   +1 more source

Beyond Charge: Field‐Effect Transistors in Multimodal Biosensing Platforms for Biomolecular Interaction Studies

Advanced Electronic Materials, EarlyView.
This review summarizes the developments in field‐effect transistor (FET)‐based dual‐mode sensor platforms and what can be learned from them. It identifies charge as a crucial factor in biomolecular interactions at interfaces, outlines the challenges of hybrid systems, and highlights their benefits.
Roger Hasler, Ciril Reiner‐Rozman, Christoph Kleber, Jakub Dostalek, Wolfgang Knoll   +4 more
wiley   +1 more source

Alcohol use disorder and associated physical health complications and treatment amongst individuals with and without opioid dependence : a case-control study

, 2018
Background: Dependence upon one substance may increase vulnerability for dependence on other substances. This study aimed to i) examine the association between opioid dependence and alcohol use and dependence; and ii) identify demographic, mental health,
Briony Larance, Elliot Nelson, Nelson, Elliot C., Larney, Sarah, Margaret Pikovsky, Conroy, Elizabeth (R16932), Amy Peacock, Louisa Degenhardt, Larance, Briony, Elizabeth Conroy, Degenhardt, Louisa, Pikovsky, Margaret, Sarah Larney, Peacock, Amy   +13 more
core   +1 more source

Genetic pre-determinants of concurrent alcohol and opioid dependence: a critical review [PDF]

, 2013
Concurrent alcohol dependence poses a significant burden to health and wellbeing of people with established opioid dependence. Although previous research indicates that both genetic and environmental risk factors contribute to the development of drug
O'Dwyer, Patrick, Dunne, Colum, Smyth, Bobby P., Martin, Marissa, Meagher, David, Cullen, Walter, O'Connor, William T., Klimas, Jan   +7 more
core   +3 more sources

Questionnaire «Opioid anosognosia» is a new tool for assessment anosognosia in opioid-dependent patients

Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
The absence of reliable, valid, and widely accepted measurement tools hinders the study of opioid anosognosia. The aim of this study: to develop, validate, and standardize a self-report questionnaire for the rapid and comprehensive assessment of opioid ...
R. D. Ilyuk, E. A. Granovskaya, V. V. Bocharov, D. I. Gromyko, A. I. Nechaeva, V. V. Pushina, A. Ya. Wuks, E. M. Krupitsky   +7 more
doaj   +1 more source