Results 121 to 130 of about 21,048 (272)

Enteric neuropathy and the vagus nerve: Therapeutic implications

open access: yesNeurogastroenterology &Motility, EarlyView.
Abstract Enteric neuropathies are characterized by abnormalities of gut innervation, which includes the enteric nervous system, inducing severe gut dysmotility among other dysfunctions. Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and ...
Bruno Bonaz
wiley   +1 more source

Effects of a new opioid peptide (Tyr-Arg) on lamina V type neurons of the rabbit spinal dorsal horn

open access: gold, 1979
Masamichi Satoh   +3 more
openalex   +1 more source

The human colon: Evidence for degenerative changes during aging and the physiological consequences

open access: yesNeurogastroenterology &Motility, EarlyView.
Reduced nociceptor innervation can explain diminished abdominal pain among the elderly. Degenerative changes occur within the colon wall, especially ascending colon. Mechanisms may include senescence‐like activity and inflammaging. Constipation is more likely to occur during age‐related challenges affecting functions of the bowel that now have reduced ...
Nicholas Baidoo, Gareth J. Sanger
wiley   +1 more source

Hyperpolarization Modulation of the T‐Type hCav3.2 Channel by Human Synenkephalin [1–53], a Shrew Neurotoxin Analogue without Paralytic Effects

open access: yesAngewandte Chemie, Volume 137, Issue 27, July 1, 2025.
Human synenkephalin [1–53] (hSYN), an analogue peptide of shrew saliva neurotoxins, was synthesized and its structural characteristics studied. Synthetic hSYN potently activated the T‐type voltage‐gated Ca channel hCav3.2 but did not paralyze mealworms. These findings offer new insight into neurological disorder treatment and evolutionary mechanisms of
Ryo Fukuoka   +5 more
wiley   +2 more sources

Opioid peptide precursors in striatum [PDF]

open access: yesFEBS Letters, 1980
K.M. Metters   +3 more
openaire   +3 more sources

Acute care of cyclic vomiting syndrome and cannabinoid hyperemesis syndrome in the home and emergency department

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 3, March 2025.
Abstract Background Cyclic vomiting syndrome (CVS) and cannabinoid hyperemesis syndrome (CHS) are both characterized by episodic, acute transitions from asymptomatic states to highly symptomatic states of nausea, repetitive vomiting, and often severe abdominal pain.
David J. Levinthal   +2 more
wiley   +1 more source

Antinociceptive and Cytotoxic Activity of Opioid Peptides with Hydrazone and Hydrazide Moieties at the C-Terminus. [PDF]

open access: yesMolecules, 2020
Dyniewicz J   +5 more
europepmc   +1 more source

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