Results 121 to 130 of about 21,048 (272)
Five Decades of Research on Opioid Peptides: Current Knowledge and Unanswered Questions. [PDF]
Fricker LD+3 more
europepmc +1 more source
Isolation and characterization of the opioid peptides from rat pituitary: beta-lipotropin.
Menachem Rubinstein+3 more
openalex +1 more source
Enteric neuropathy and the vagus nerve: Therapeutic implications
Abstract Enteric neuropathies are characterized by abnormalities of gut innervation, which includes the enteric nervous system, inducing severe gut dysmotility among other dysfunctions. Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and ...
Bruno Bonaz
wiley +1 more source
Effects of a new opioid peptide (Tyr-Arg) on lamina V type neurons of the rabbit spinal dorsal horn
Masamichi Satoh+3 more
openalex +1 more source
The human colon: Evidence for degenerative changes during aging and the physiological consequences
Reduced nociceptor innervation can explain diminished abdominal pain among the elderly. Degenerative changes occur within the colon wall, especially ascending colon. Mechanisms may include senescence‐like activity and inflammaging. Constipation is more likely to occur during age‐related challenges affecting functions of the bowel that now have reduced ...
Nicholas Baidoo, Gareth J. Sanger
wiley +1 more source
Human synenkephalin [1–53] (hSYN), an analogue peptide of shrew saliva neurotoxins, was synthesized and its structural characteristics studied. Synthetic hSYN potently activated the T‐type voltage‐gated Ca channel hCav3.2 but did not paralyze mealworms. These findings offer new insight into neurological disorder treatment and evolutionary mechanisms of
Ryo Fukuoka+5 more
wiley +2 more sources
Opioid peptide precursors in striatum [PDF]
K.M. Metters+3 more
openaire +3 more sources
Abstract Background Cyclic vomiting syndrome (CVS) and cannabinoid hyperemesis syndrome (CHS) are both characterized by episodic, acute transitions from asymptomatic states to highly symptomatic states of nausea, repetitive vomiting, and often severe abdominal pain.
David J. Levinthal+2 more
wiley +1 more source
Antinociceptive and Cytotoxic Activity of Opioid Peptides with Hydrazone and Hydrazide Moieties at the C-Terminus. [PDF]
Dyniewicz J+5 more
europepmc +1 more source