Results 51 to 60 of about 21,347 (246)
Perspectives on Endogenous Opioids in Birds
Frontiers in Physiology, 2018 The present review summarizes the state of knowledge of endogenous opioids in birds. Endogenous opioid peptides acts in a neuromodulatory, hormonal and paracrine manner to mediate analgesic and other physiological functions.
Colin G. Scanes +1 more
doaj +1 more source
Concomitant duplications of opioid peptide and receptor genes before the origin of jawed vertebrates. [PDF]
PLoS ONE, 2010 BACKGROUND: The opioid system is involved in reward and pain mechanisms and consists in mammals of four receptors and several peptides. The peptides are derived from four prepropeptide genes, PENK, PDYN, PNOC and POMC, encoding enkephalins, dynorphins ...
Görel Sundström +2 more
doaj +1 more source
Drug Testing and Analysis, EarlyView.Eight metabolites for N‐pyrrolidino fluetonitazene were identified in vitro, three of which (M2, M6 and M8) were present in an authentic urine sample. M2 was the most abundant in vivo metabolite and is a common marker metabolite of nitazepyne‐type substances.
Severin Zemp +6 more
wiley +1 more source
Hemorphins—From Discovery to Functions and Pharmacology
Molecules, 2021 During the last three decades, a variety of different studies on bioactive peptides that are opioid receptor ligands, have been carried out, with regard to their isolation and identification, as well as their molecular functions in living organisms. Thus,
Przemyslaw Mielczarek +7 more
doaj +1 more source
GLP‐1 Receptor Agonism Exacerbates Activity‐Based Anorexia in Mice
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Glucagon‐like peptide‐1 receptor (GLP‐1R) agonists reduce food intake and body weight, suggesting they should be avoided in anorexia nervosa. However, preclinical evidence that these drugs reduce activity and reward‐seeking behavior raises the possibility that they might attenuate the compulsive‐like hyperactivity central to ABA ...
Amit Thakar +2 more
wiley +1 more source
, 1982 Bovine adrenal medullary chromaffin cells were used to study the relationship between opioid peptide and catecholamine secretion from the adrenal medulla.
KJ Chang, OH Viveros, SP Wilson
core +1 more source
Food Biomacromolecules, EarlyView.Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley +1 more source
Do Inhalation General Anesthetic Drugs Induce the Neuronal Release of Endogenous Opioid Peptides?
, 2005 The antagonism of some effects of inhalation general anesthetic agents by naloxone suggests that there may be an opioid component to anesthetic action.
Quock, Raymond M +3 more
core +2 more sources
Frontiers in Behavioral Neuroscience, 2013 Significant evidence implicates the endogenous opioid system (opioid peptides and receptors) in the mechanisms underlying the psychopharmacological effects of ethanol.
Laura eFont +2 more
doaj +1 more source
Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary
Interdisciplinary Medicine, EarlyView.This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng +9 more
wiley +1 more source