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Opioid analgesics for nociceptive cancer pain: A comprehensive review
Ca-A Cancer Journal for CliniciansChristina Abdel Shaheed +2 more
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Homeostatic scaling of dynorphin signaling by a non-canonical opioid receptor [PDF]
Nature CommunicationsThe endogenous opioid system provides powerful control over emotions, nociception, and motivation among many other fundamental nervous system functions.
Xiaona Li +10 more
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Insights into the interaction between hemorphins and δ-opioid receptor from molecular modeling [PDF]
Frontiers in Molecular BiosciencesHemorphins are short atypical opioid peptide fragments embedded in the β-chain of hemoglobin. They have received considerable attention recently due to their interaction with opioid receptors.
Priya Antony +4 more
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IUPHAR themed review: Opioid efficacy, bias, and selectivity
Pharmacological Research, 2023 Drugs acting at the opioid receptor family are clinically used to treat chronic and acute pain, though they represent the second line of treatment behind GABA analogs, antidepressants and SSRI’s.
Nokomis Ramos-Gonzalez +2 more
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Opportunities and Challenges for In Silico Drug Discovery at Delta Opioid Receptors
Pharmaceuticals, 2022 The delta opioid receptor is a Gi-protein-coupled receptor (GPCR) with a broad expression pattern both in the central nervous system and the body. The receptor has been investigated as a potential target for a multitude of significant diseases including ...
Yazan J. Meqbil, Richard M. van Rijn
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