Results 181 to 190 of about 2,594,817 (409)

Efficacy and Safety of Lisdexamfetamine Versus Topiramate Versus Naltrexone/Bupropion in Individuals With Binge Eating Disorder: A Network Meta‐Analysis

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of lisdexamfetamine, topiramate, and naltrexone/bupropion for treating binge eating disorder (BED) using network meta‐analysis. Method We systematically searched PubMed, Scopus, ClinicalTrials.gov, and Cochrane Central up to February 2025 for randomized controlled trials evaluating these medications
Tamer Hodrob   +5 more
wiley   +1 more source

Vanillin Modulates the Sedative Effect of Diazepam, Possibly Through GABAergic Interaction Pathways in Thiopental Sodium‐Induced Sleeping Mice

open access: yesFood Safety and Health, EarlyView.
Vanillin showed moderate sedative and modulatory synergistic activities on diazepam in thiopental sodium‐induced sleeping mice. These effects are implicated with GABAergic intervention. ABSTRACT Insomnia is a common sleep disorder affecting approximately 10% of adults.
Salehin Sheikh   +8 more
wiley   +1 more source

Insights into the interaction between hemorphins and δ-opioid receptor from molecular modeling

open access: yesFrontiers in Molecular Biosciences
Hemorphins are short atypical opioid peptide fragments embedded in the β-chain of hemoglobin. They have received considerable attention recently due to their interaction with opioid receptors.
Priya Antony   +4 more
doaj   +1 more source

Synthesis and Evaluation of a Novel Bivalent Selective Antagonist for the Mu-Delta Opioid Receptor Heterodimer that Reduces Morphine Withdrawal in Mice

open access: green, 2018
Keith M. Olson   +5 more
openalex   +1 more source

Effects of Long‐Term Exposure to the Earned Income Tax Credit on Work Disability in Later Life

open access: yesHealth Economics, EarlyView.
ABSTRACT This study investigates the impact of the Earned Income Tax Credit (EITC) on work disability and Social Security Disability Insurance (DI) claims among Americans. Utilizing the Panel Study of Income Dynamics, we examine the effects of EITC exposure from birth to mid‐adulthood on work disability risk before retirement. Our analysis reveals that
Katie Jajtner   +2 more
wiley   +1 more source

Author response for "Chronic stress differentially alters mRNA expression of opioid peptides and receptors in the dorsal hippocampus of female and male rats"

open access: gold, 2021
Megan A. Johnson   +8 more
openalex   +1 more source

Spirocyclic Diamine Scaffolds for Medicinal Chemistry

open access: yesHelvetica Chimica Acta, EarlyView.
Here we enumerated 391 spirocyclic diamine drug scaffolds with ring sizes four to eight and found that most of them are unknown. We prepared four novel such spirocycles and discovered a micromolar inhibitor of the M4 muscarinic receptor. ABSTRACT Medicinal chemistry requires the exploration of structurally diverse compound families to expand the ...
Aline Carrel   +3 more
wiley   +1 more source

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