Results 221 to 230 of about 2,513,925 (427)

Identification and Investigation of the Intrinsic Receptor Activation Potential and Metabolization of the New Oxo‐Pyridyl Synthetic Cannabinoid Receptor Agonist CH‐FUBBMPDORA

open access: yesDrug Testing and Analysis, EarlyView.
Another Chinese generic ban‐evading SCRA, CH‐FUBBMPDORA, has emerged. This study reports its first identification in Europe, its analytical characterization (NMR, Raman, FTIR, GC–MS, and HRMS), its cannabinoid activation potential in a βarr2 recruitment assay, and its metabolization profile.
Marie H. Deventer   +13 more
wiley   +1 more source

Screening and Quantification of the Synthetic Cannabinoid Receptor Agonist 5F‐MDMB‐PINACA From Seized Prison Paper Using Ultraperformance Liquid Chromatography–Mass Spectrometry Approaches

open access: yesDrug Testing and Analysis, EarlyView.
Synthetic cannabinoid receptor agonists are being infused on paper and illicitly introduced into prisons through mail correspondence. An approach to quantify and map the synthetic cannabinoid 5F‐ADB on a seized paper sample from a UK prison was determined using ultraperformance liquid chromatography–quadrupole Dalton–mass spectrometry.
Giorgia Vaccaro   +4 more
wiley   +1 more source

Molecular Determinants of Receptor Affinity and Selectivity of the Natural Δ-Opioid Agonist, Dermenkephalin

open access: hybrid, 1989
Sandrine Sagan   +5 more
openalex   +1 more source

Effects of Dimenhydrinate on Motor Behavior and Vascular Function: Possible Implications for the Field of Sports

open access: yesDrug Testing and Analysis, EarlyView.
Regarding cardiovascular effects, DMH decreased vascular reactivity to phenylephrine and acetylcholine. We observed that the combination of DPH and 8‐Cl‐T was identified as the responsible for increasing blood pressure and heart rate in the biological model used.
Jazmín Flores‐Monroy   +3 more
wiley   +1 more source

Cross‐Cultural Validation of the Binge Eating Disorder Screener‐7 (BEDS‐7) Across 42 Countries

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study aimed to evaluate the reliability and validity of the Binge Eating Disorder Screener‐7 (BEDS‐7) across 42 countries and 26 languages, assessing its reliability and validity as a screening tool for binge‐eating disorder (BED) in diverse cultural contexts.
Ateret Gewirtz‐Meydan   +70 more
wiley   +1 more source

New cardiovascular biomarkers in patients with advanced cancer – A prospective study comparing MR‐proADM, MR‐proANP, copeptin, high‐sensitivity troponin T and NT‐proBNP

open access: yesEuropean Journal of Heart Failure, EarlyView.
(A) Univariable receiver operating characteristic (ROC) curves for all biomarkers. (B) Kaplan–Meier curves for best cut‐point of mid‐regional pro‐adrenomedullin (MR‐proADM) for survival (n = 442). AUC, area under the curve; CI, confidence interval; HR, hazard ratio; hsTnT, high‐sensitivity troponin T; MR‐proANP, mid‐regional pro‐atrial natriuretic ...
Markus S. Anker   +18 more
wiley   +1 more source

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