Results 221 to 230 of about 86,994 (313)

Characteristics of methamphetamine‐related deaths in the United Kingdom, 1997–2024

Addiction, EarlyView.
Abstract Background and aims People who use methamphetamine have a standardised mortality ratio 6.8 times greater than the general population, with several countries reporting concerning increases in methamphetamine‐related mortality over the past decade.
Emmert Roberts, Rebecca McKetin, Caroline Copeland   +2 more
wiley   +1 more source

Mu opioid receptor activation in microglia enhances HIV-1 infection and HIV-infection-induced inflammatory responses. [PDF]

Front Immunol
Skeete C, Sgambettera G, Gojanovich AD, He X, Bryant D, Yang M, Banerjee S, Quiñones-Molina AA, Akiyama H, Mostoslavsky G, Henderson AJ, Gummuluru S.   +11 more
europepmc   +1 more source

Contingency management interventions for substance use and addictive behaviours: Review of the United Kingdom evidence base

Addiction, EarlyView.
Abstract Background and aims Substance use and other addictive behaviours including gambling remain major public health concerns in the UK. Despite the effectiveness of substance use treatment approaches, treatment adherence and success rates remain low.
Carol‐Ann Getty, Tricia McQuarrie, Eileen Brobbin   +2 more
wiley   +1 more source

<i>Kappa</i>-opioid receptor gene (<i>OPRK1</i>) variations associated with opioid abstinence behaviors among chronic heroin users. [PDF]

Front Pharmacol
Greenwald MK, Demery C, Moses TEH, Burmeister M.   +3 more
europepmc   +1 more source

Targeted Opioid Receptor Antagonists in the Treatment of Alcohol Use Disorders

, 2013
Mark J. Niciu, Albert J. Arias
openalex   +1 more source

Drug use among people in prison: A global review of epidemiology, harms and interventions

Addiction, EarlyView.
Abstract Background and aims People who use drugs are overrepresented in the criminal justice system. We aimed to provide a broad synthesis of the epidemiology, harms and interventions related to drug use and drug use disorders among incarcerated adults worldwide, and highlight gaps in evidence and practice.
Louis Favril, John Strang, Seena Fazel
wiley   +1 more source

Molecular and cellular basis of mu-opioid receptor signaling: mechanisms underlying tolerance and dependence development. [PDF]

Front Neurosci
Swingler M, Donadoni M, Unterwald EM, Maggirwar SB, Sariyer IK.   +4 more
europepmc   +1 more source

Substance Use and Sex Index version 2 (SUSI‐2): Validation of a brief questionnaire for the measurement of behaviours associated with transmission of blood borne viruses and sexually transmitted infections

Addiction, EarlyView.
Abstract Aims This study sought to validate a community‐acceptable Substance Use & Sex Index (SUSI) for use in substance use intervention research. SUSI aims to measure behaviours associated with the transmission of blood‐borne viruses (BBV) and sexually transmitted infections (STI) among people who use substances and incorporate contemporary sexual ...
Brendan Clifford, Raimondo Bruno, Liam Acheson, Michael E. Cecilio, Krista J. Siefried, Jack Freestone, Vincent J. Cornelisse, Brendan Crozier, Nicky Bath, Nadine Ezard   +9 more
wiley   +1 more source

Evidencing the role of a conserved polar signaling channel in the activation mechanism of the μ-opioid receptor. [PDF]

Comput Struct Biotechnol J
Sarkar A, Dvorácskó S, Lipinszki Z, Mitra A, Harmati M, Buzás K, Borics A.   +6 more
europepmc   +1 more source

Exploring the genetic overlap between substance use disorder and educational attainment

Addiction, EarlyView.
Abstract Background and aims Substance use disorder (SUD) is a polygenic psychiatric condition characterized by persistent drug use despite negative consequences. Several studies support that higher cognitive performance and educational attainment (EA) are associated with a reduced risk for SUD.
Judit Cabana‐Domínguez, Laura Vilar‐Ribó, María Soler Artigas, Silvia Alemany, Natalia Llonga, Pau Carabí‐Gassol, Uxue Zubizarreta‐Arruti, Valeria Macias‐Chimborazo, Lara Grau‐López, Constanza Daigre, Elena Ros‐Cucurull, Raúl Felipe Palma‐Alvarez, Germán Ortega‐Hernández, Noèlia Fernàndez‐Castillo, Bru Cormand, Josep Antoni Ramos‐Quiroga, Marta Ribasés   +16 more
wiley   +1 more source