Results 251 to 260 of about 2,594,817 (409)

The mu opioid receptor: A new target for cancer therapy?

Cancer, 2015
P. Singleton, J. Moss, D. Karp, J. Atkins, F. Janku   +4 more
semanticscholar   +1 more source

Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease

Movement Disorders, EarlyView.
Abstract Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abundantly expressed in MSNs, is a promising biomarker of striatal integrity, but region‐specific associations and its potential for early‐stage ...
Mena Farag, Michael J. Murphy, Nicola Z. Hobbs, Michela Leocadi, Kate Fayer, Olivia Thackeray, Johan Gobom, Marc Ciosi, Amanda Heslegrave, Henrik Zetterberg, Douglas R. Langbehn, Darren G. Monckton, Edward J. Wild, Sarah J. Tabrizi, Rachael I. Scahill   +14 more
wiley   +1 more source

Dynamics of agonist-evoked opioid receptor activation revealed by FRET- and BRET-based opioid receptor conformation sensors. [PDF]

Commun Biol
Kirchhofer SB, Kurz C, Geier L, Krett AL, Krasel C, Bünemann M.   +5 more
europepmc   +1 more source

Molecular Regulation of Opioid Receptor Signaling

, 2012
Selena S. Schattauer
openalex   +1 more source

Libidibia ferreaMature Seeds Promote Antinociceptive Effect by Peripheral and Central Pathway: Possible Involvement of Opioid and Cholinergic Receptors

, 2014
Luis Armando Sawada, Vanessa Sâmia da Conçeição Monteiro, Guilherme Rodrigues Rabelo, Germana Bueno Dias, Maura Da Cunha, José Luíz Martins do Nascimento, Gilmara de Nazareth Tavares Bastos   +6 more
openalex   +1 more source

Different mechanisms of homologous and heterologous μ‐opioid receptor phosphorylation

British Journal of Pharmacology, 2015
Anika Mann, Susann Illing, E. Miess, S. Schulz   +3 more
semanticscholar   +1 more source

Correlates of Positive Response to Therapeutic Hydrodistension in Interstitial Cystitis/Bladder Pain Syndrome

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims The objective of this study was to assess the duration and clinical correlates of positive response in interstitial cystitis/bladder pain syndrome patients undergoing therapeutic bladder hydrodistension (HOD) or HOD with electrofulguration (for those with Hunner lesions).
Dylan T. Wolff, Carl D. Langefeld, Julie T. Call, Gopal Badlani, Robert J. Evans, Stephen J. Walker   +5 more
wiley   +1 more source

Comparison of ventilatory depression by carfentanil, fentanyl, and heroin, and reversal by opioid receptor antagonists in rats. [PDF]

Neuropharmacology
Flynn SM, France CP.
europepmc   +1 more source

Novel GPCR paradigms at the μ‐opioid receptor

British Journal of Pharmacology, 2015
Georgina L. Thompson, E. Kelly, A. Christopoulos, Meritxell Canals   +3 more
semanticscholar   +1 more source

Innovation in Rural Nonprofits: Which Organizational Capacities Matter Most?

Nonprofit Management and Leadership, EarlyView.
ABSTRACT This research note draws on theory and empirical research from the broader fields of management, organizational capacity, and innovation to examine how specific organizational capacities relate to innovation in a sample of 107 rural nonprofit organizations in a Southeastern U.S. state.
Kristina Jaskyte, Ashley Hunter, Lina Danusevičienė   +2 more
wiley   +1 more source