Results 111 to 120 of about 226,084 (315)

Contemporary and Emerging Therapies in the Management of Refractory Angina: A Clinical Review

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Refractory angina (RA) represents a growing challenge in clinical cardiology, particularly in patients with obstructive coronary artery disease (CAD) who remain symptomatic despite optimal medical therapy and who are not candidates for revascularization.
Alex Angers‐Goulet, Siddhartha Mengi, David Garcia Labbé, Can Manh Nguyen, Jean‐Michel Paradis   +4 more
wiley   +1 more source

Use patterns of classic, novel, and herbal opioids

Emerging Trends in Drugs, Addictions, and Health
Background: Data on use patterns and psychological and physical effects of novel synthetic opioids (NSOs) and herbal opioids like kratom (Mitragyna speciosa) lags behind that of classic opioids.
Elisabeth Prevete, Natasha L. Mason, Kim P． C． Kuypers, Eef L. Theunissen, Pablo Mallaroni, Massimo Pasquini, Johannes G. Ramaekers   +6 more
doaj   +1 more source

Easier, Safer, and Greener: Unlocking the Power of Solid Reagents in Organic Reactions by Mechanochemistry

ChemistryEurope, EarlyView.
This review highlights the powerful synergy between mechanochemistry and solid reagents to replace hazardous substances traditionally used in organic synthesis. Such an approach offers a safer and more sustainable pathway for conducting organic reactions, with potential benefits in both reactivity and selectivity. The use of solid bases, acids, and gas
Adrien Gallego, Nicolas Pétry, Julien Pinaud, Olivia Giani, Frédéric Lamaty   +4 more
wiley   +1 more source

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

Chemistry – A European Journal, EarlyView.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati, Claudio Trapella, Vinicio Zanirato, Virginia Cristofori, Anna Fantinati   +4 more
wiley   +1 more source

Treatment utilization among persons with opioid use disorder in the United States

, 2016
Li‐Tzy Wu, He Zhu, Marvin S. Swartz
openalex   +1 more source

Modeling Supports Combinatorial Effects Between Pharmacological and Non‐Pharmacological Interventions to Prevent Opioid‐Induced Cardiac Arrest

Clinical Pharmacology &Therapeutics, EarlyView.
Few studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Bradlee Thrasher, John Mann, Anik Chaturbedi, Shilpa Chakravartula, Hamed Meshkin, Affan Affan, Alexander Galluppi, Ji Young Kim, Nigar Karimli, Yue Han, Zachary Dezman, Jeffry Florian, Zhihua Li   +12 more
wiley   +1 more source

Synthetic illicit opioids in Brazil: Nitazenes arrival

Forensic Science International: Reports
Purpose: While illicit opioids have not been historically significant in Brazil, these numbers have increased in the last few years. This change in the drug scenario is mainly associated with synthetic opioids, a class of new psychoactive substances (NPS)
Karen Rafaela Gonçalves de Araújo, André Luis Fabris, Luiz Ferreira Neves Junior, Alexandre Learth Soares, Jose Luiz Costa, Mauricio Yonamine   +5 more
doaj   +1 more source

Identification and Structural Elucidation of a New Synthetic Cannabinoid, MDMB‐5′Br‐PINACA, in Seized Herbal Materials

Drug Testing and Analysis, EarlyView.
MDMB‐5Br‐PINACA, a novel synthetic cannabinoid, was identified and structurally characterized in seized herbal products using GC‐MS, LC‐HRMS, and NMR. The discovery underscores ongoing diversification of SCs and the need for vigilant surveillance.
Alexandre Barcia de Godoi, Lucas André Zeoly, Rafael Lanaro, Ingrid Simões Oliveira, Mariana Cepollaro Diana, Mauricio Yonamine, Jose Luiz Costa   +6 more
wiley   +1 more source

Association Between Pain Intensity and Discontinuing Opioid Therapy or Transitioning to Intermittent Opioid Therapy After Initial Long-Term Opioid Therapy: A Retrospective Cohort Study [PDF]

, 2021
Corey J. Hayes, Erin E. Krebs, Joshua D. Brown, Chenghui Li, Teresa J. Hudson, Bradley C. Martin   +5 more
openalex   +1 more source

Efficacy and Safety of Lisdexamfetamine Versus Topiramate Versus Naltrexone/Bupropion in Individuals With Binge Eating Disorder: A Network Meta‐Analysis

European Eating Disorders Review, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of lisdexamfetamine, topiramate, and naltrexone/bupropion for treating binge eating disorder (BED) using network meta‐analysis. Method We systematically searched PubMed, Scopus, ClinicalTrials.gov, and Cochrane Central up to February 2025 for randomized controlled trials evaluating these medications
Tamer Hodrob, Ibrahim Ismail, Alaaeddin Abusalameh, Celina R. Andonie, Omar Ayesh, Hazem Ayesh   +5 more
wiley   +1 more source