Results 101 to 110 of about 4,457,338 (303)

Pomegranate fruit juice adulteration with apple juice: detection by UV–visible spectroscopy combined with multivariate statistical analysis

Scientific Reports, 2022
Pomegranate is rich in high value nutritional substances known to be beneficial against several diseases and its use in medicine is known since ancient times.
Lucia Pappalardo
doaj   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC‐I Antigen Presentation That Promotes Tumor Immune Evasion

Advanced Science, EarlyView.
ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao, Linlin Sheng, Jianhao Qiu, Junjie Ma, Kai Jin, Binggong Zhao, Tianrun Miao, Jing Chen, Yehong Li, Zhan Zhang, Dongfeng Sun, Yongmeng Li, Hui Tian   +12 more
wiley   +1 more source

Chemometrics Analysis of the Components of Artemisia dracunculus L. Essential Oil with Growth Time

Liang you shipin ke-ji
To explore the differences in the quality of Artemisia dracunculus L essential oil at different growth times, gas chromatography-mass spectrometry (GC-MS) was used to analyze the chemical components of Artemisia annua essential oil.
SUN Yi-ming, YANG Jia-lu, HOU Chun-jing, LI Shou-zhu, WANG Lin-qing, GAO Han-ze   +5 more
doaj   +1 more source

Metabolic fingerprint after acute and under sustained consumption of a functional beverage based on grape skin extract in healthy human subjects [PDF]

, 2015
Grape-derived polyphenols are considered to be one of the most promising ingredients for functional foods due to their health-promoting activities. We applied a HPLC-MS-based untargeted metabolomic approach in order to evaluate the impact of a functional
Andrés Lacueva, Ma. Cristina, Khymenets, Olha, Llorach, Rafael, Mercader-Martí, M., Reglero, Guillermo, Torres, Mireia, Urpí Sardà, Mireia, Vázquez Fresno, Rosa   +7 more
core   +1 more source

Non-Halal Gelatin Prediction: A Comparative Machine Learning Analysis between OPLS–DA and ANN Models

Sains Malaysiana
Gelatin is derived from animal collagen, sourced primarily from bovine or porcine, and finds widespread application within the food industry. These issues raise concern over its halal status, particularly among Muslims and Jews, as they adhere to dietary laws prohibiting the consumption of pork and its derivatives.
Mohd Hafis Yuswan, Norazlina Ali, Syaiful Izwan Ismail, Basyirah Muda, Mohamad Habeeb Helmy Idris, Mazidah Md Nor, Nur Suhadah Nawi, Muhamad Shirwan Abdullah Sani, Kok Song Lai   +8 more
openaire   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

Advanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu, Abudureyimujiang Aili, Zheng Kuang, Liting Cao, Zemin Li, Ying Shang, Yingying Ge, Tingting Hu, Yongchang Sun, Wuli Zhao, Rong Jin, Chun Chang   +11 more
wiley   +1 more source

Untargeted Metabolomics Analysis Reveals the Effect of Fixation on the Profile of Volatile Compounds of Cyclocarya paliurus Tea

Polish Journal of Food and Nutrition Sciences
Fixation is a necessary tea processing step that affects the quality of tea, including its aroma. However, there are no guidelines to follow whether the Cyclocarya paliurus leaves need to be fixated to produce tea.
Minge Bai, Liling Wang
doaj   +1 more source

PLS-based and regularization-based methods for the selection of relevant variables in non-targeted metabolomics data

Frontiers in Molecular Biosciences, 2016
Non-targeted metabolomics constitutes a part of systems biology and aims to determine many metabolites in complex biological samples. Datasets obtained in non-targeted metabolomics studies are multivariate and high-dimensional due to the sensitivity of ...
Renata Bujak, Emilia Daghir-Wojtkowiak, Roman Kaliszan, Michal Jan Markuszewski   +3 more
doaj   +1 more source