Results 31 to 40 of about 28,317 (243)

Evaluating the physiological and biochemical responses of melon plants to NaCl salinity stress using supervised and unsupervised statistical analysis

open access: yesPlant Stress, 2022
Salinity is a major environmental issue affecting plant production, particularly in the Middle East. Multivariate data analysis including principal component analysis (PCA), hierarchical clustering analysis (HCA), and orthogonal projections to latent ...
Behrooz Sarabi, Jaleh Ghashghaie
doaj   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao   +8 more
wiley   +1 more source

Evaluation of Internet-based pharmaceutical care effect on young and middle-aged patients with hypertension by the principal component analysis and the Markov cohort during COVID-19 pandemic

open access: yesHealth and Quality of Life Outcomes, 2023
Background Pharmaceutical care has the potential to improve hypertension control rates in young and middle-aged patients. Due the COVID-19 epidemic, standard intervention methods may not be applicable.
Xinmei Li   +8 more
doaj   +1 more source

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao   +8 more
wiley   +1 more source

Prediction of Antimicrobial and Antioxidant Activities of Mexican Propolis by 1H-NMR Spectroscopy and Chemometrics Data Analysis

open access: yesMolecules, 2017
A feasibility study to predict antimicrobial and antioxidant activity properties of propolis extracts using 700-MHz 1H-NMR spectra and multivariate regression data analysis is presented.
J. Fausto Rivero-Cruz   +6 more
doaj   +1 more source

Machine Learning‐Informed Nano Co‐Assembly Inhibits Fibroblast Activation Protein and Improves Drug Delivery in Fibrotic Tissue

open access: yesAdvanced Materials, EarlyView.
We present SP‐13786 (SP), a fibroblast activation protein (FAP) inhibitor, as a universal excipient for co‐assembling stable drug nanoparticles (SCAN). Assembly mechanism deciphered by molecular dynamics and explainable machine learning, SCAN attenuate fibrosis‐induced stromal barriers, enhances lesional drug accumulation, and improves therapeutic ...
Zehua Liu   +15 more
wiley   +1 more source

Structural, Microstructural, Elastic, and Microplastic Properties of Aluminum Wires (from AAAC (A50) Cables) after Fatigue Tests

open access: yesMetals, 2023
Single Al wires from unused AAAC (A50) cables were studied after laboratory fatigue testing, which simulated processes arising in these wires during their operation in the cables of overhead power lines (OPLs) and are valuable for predicting the lifespan
Aleksandr A. Levin   +11 more
doaj   +1 more source

Interfacial Behavior of Methane in Methane/p‐Xylene/Water Systems: First Principles Inspected Using Neutron Imaging and Molecular Dynamics Simulations

open access: yesAdvanced Materials Interfaces, EarlyView.
Pressurized gases reduce interfacial tension (IFT) at the gas‐liquid interfaces, their influence on the liquid–liquid interfaces remains unclear. For model compounds methane, water, and p‐xylene, neutron imaging observation of pressurized three‐phase systems is combined with Molecular Dynamics simulations.
Martin Melčák   +8 more
wiley   +1 more source

Enhanced Infection Resistance and Regenerative Healing of Titanium Implants via Peptide‐Loaded Biodegradable Coatings

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li   +7 more
wiley   +1 more source

Osteopenia-osteoporosis discrimination in postmenopausal women by 1H NMR-based metabonomics.

open access: yesPLoS ONE, 2019
This is a report on how 1H NMR-based metabonomics was employed to discriminate osteopenia from osteoporosis in postmenopausal women, identifying the main metabolites associated to the separation between the groups. The Assays were performed using seventy-
T A Pontes   +4 more
doaj   +1 more source

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