Results 51 to 60 of about 1,103,257 (330)

Orbital apex cyst: a rare cause of compressive optic neuropathy post-functional endoscopic sinus surgery [PDF]

, 2017
There are various causes that can lead to compressive optic neuropathy. We present here orbital apex cyst as an unusual cause of compressive optic neuropathy in a 49-year-old male.
Embong, Zunaina, Pathma, Letchumanan, Shu, Fen Ho, Singh, Harvinder, Yi, Ni Koh   +4 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Ischemic injury leads to extracellular matrix alterations in retina and optic nerve

Scientific Reports, 2017
Retinal ischemia occurs in a variety of eye diseases. Restrained blood flow induces retinal damage, which leads to progressive optic nerve degeneration and vision loss.
J. Reinhard, M. Renner, Susanne Wiemann, Daniel A. Shakoor, G. Stute, H. B. Dick, A. Faissner, Stephanie C. Joachim   +7 more
semanticscholar   +1 more source

Prostatic Carcinoma Metastatic to the Optic Nerve [PDF]

, 2009
Optic nerve can be infiltrated with various tumors and inflammatory processes, with a considerable prevalence of primary over secondary tumors. Metastases of gastric carcinoma to the optic nerve are less frequently, and those of prostatic carcinoma very ...
Branimir Cerovski, Neda Stiglmayer, Smiljka Popović Suić, Tomislav Vidović   +3 more
core   +1 more source

Histone deacetylase expression patterns in developing murine optic nerve [PDF]

, 2014
BACKGROUND: Histone deacetylases (HDACs) play important roles in glial cell development and in disease states within multiple regions of the central nervous system. However, little is known about HDAC expression or function within the optic nerve.
Deborah C Otteson, Mahesh Shivanna, Sarika Tiwari, Subramanian Dharmarajan, Teri L Belecky-Adams   +4 more
core   +2 more sources

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

Macular ganglion cell complex layer thickness measured with spectral-domain OCT in a large population-based cohort study

BMC Ophthalmology
Purpose To establish the normal GCC thickness profile in the general population using SD-OCT in different macular sectors. Determining the systemic and ophthalmic factors associated with GCC thickness and further identifying the potential risk factors ...
Caixia Lin, Lixia Ma, Aiguo Lv, Hongyi Liu, Qing Pan, Kai Cao, Xu Jia, Sujie Fan, Jian Wu, Ningli Wang   +9 more
doaj   +1 more source

OCT for glaucoma diagnosis, screening and detection of glaucoma progression. [PDF]

, 2013
Optical coherence tomography (OCT) is a commonly used imaging modality in the evaluation of glaucomatous damage. The commercially available spectral domain (SD)-OCT offers benefits in glaucoma assessment over the earlier generation of time domain-OCT due
Bussel, Igor I, Schuman, Joel S, Wollstein, Gadi   +2 more
core   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Avoiding Clinical Misinterpretation and Artifacts of Optical Coherence Tomography Analysis of the Optic Nerve, Retinal Nerve Fiber Layer, and Ganglion Cell Layer

Journal of neuro-ophthalmology, 2016
Background:Optical coherence tomography (OCT) has become an important tool for diagnosing optic nerve disease. The structural details and reproducibility of OCT continues to improve with further advances in technology.
John J. Chen, R. Kardon
semanticscholar   +1 more source