Results 71 to 80 of about 2,927 (186)

Optic Disc Pallor in Parkinson's Disease: A UK Biobank Study

open access: yesMovement Disorders, Volume 40, Issue 6, Page 1123-1133, June 2025.
Abstract Background Recent studies have suggested that retinal changes measured with optical coherence tomography are detectable in early Parkinson's disease (PD), highlighting the potential of ophthalmic biomarkers for diagnosis and monitoring. Objective We set out to investigate the relationship between optic disc pallor measured in fundoscopy images
Samuel Gibbon   +3 more
wiley   +1 more source

Evaluating the Therapeutic Potential of Superoxide Dismutase in a Rat Model of Wet Age‐Related Macular Degeneration

open access: yesFASEB BioAdvances, Volume 7, Issue 6, June 2025.
Oral Superoxide Dismutase Therapy Mitigates Choroidal Neovascularization in a Laser‐Induced Rat Model of Wet Age‐Related Macular Degeneration. Oral Administration of GF103, a Superoxide Dismutase From Bacillus amyloliquefaciens, Reduces Choroidal Neovascularization (CNV) in a Laser‐Induced CNV Rat Model.
Hyun Chul Jeong   +4 more
wiley   +1 more source

Microvascular Changes Associated with Optic Disc Drusen: Case Report

open access: yesTürk Oftalmoloji Dergisi, 2019
Optic disc drusen (ODD) is an important clinical entity that is sometimes misdiagnosed as papilledema because of elevated and blurred disc margins. A 17-year-old male who presented with headaches underwent detailed ophthalmological examination as well as
Özlem Biçer, Huban Atilla
doaj   +1 more source

Activated mTOR Signaling in the RPE Drives EMT, Autophagy, and Metabolic Disruption, Resulting in AMD‐Like Pathology in Mice

open access: yesAging Cell, Volume 24, Issue 6, June 2025.
Our study reveals that overactivation of both mTOR complexes through mLST8 in RPE cells triggers AMD‐like pathology and cellular dysfunction. This finding highlights the critical role of balanced mTOR signaling in retinal health and suggests that targeting both complexes could be therapeutic for AMD treatment.
Olivia Chowdhury   +27 more
wiley   +1 more source

Do Optic Disc Drusen Cause Unilateral Nyctalopia

open access: yesCase Reports in Ophthalmology, 2010
This is a case report of a patient with unilateral nyctalopia in whom ipsilateral optic disc drusen were the only finding despite extensive investigation.
Yi Wei Goh, Alex Buller
doaj   +1 more source

Peripapillary choroidal vascularity of paediatric myopic eyes with peripapillary hyperreflective ovoid mass‐like structures

open access: yesActa Ophthalmologica, Volume 103, Issue 2, Page e94-e103, March 2025.
Abstract Purpose To assess the peripapillary choroidal vasculature in paediatric myopic patients with and without peripapillary hyperreflective ovoid mass‐like structures (PHOMS). Methods This prospective study includes 60 eyes of 60 myopic (spherical equivalent [SE] <−1.00 dioptre [D]) patients with (n = 30) and without (n = 30) PHOMS (PHOMS [+] and ...
Furkan Kirik   +6 more
wiley   +1 more source

Retinal thinning differentiates treatment effects in relapsing multiple sclerosis below the clinical threshold

open access: yesAnnals of Clinical and Translational Neurology, Volume 12, Issue 2, Page 345-354, February 2025.
Abstract Objective To investigate retinal layer thinning as a biomarker of disease‐modifying treatment (DMT) effects in relapsing multiple sclerosis (RMS). Methods From an ongoing prospective observational study, we included patients with RMS, who (i) had an optical coherence tomography (OCT) scan within 6 to 12 months after DMT start (rebaseline) and ≥
Gabriel Bsteh   +20 more
wiley   +1 more source

The influence of topical antiglaucoma drugs on the reduction of the decrease of visual field sensitivity due to optic nerve head drusen: Case report [PDF]

open access: diamond, 2022
Marija Radenković   +5 more
openalex   +1 more source

Bilateral presumed astrocytic hamartomas in a patient with retinitis pigmentosa

open access: yesClinical Ophthalmology, 2011
Michael Kinori1, Iris Moroz1,2, Ygal Rotenstreich1,2, Hagith Yonath2,3, Ido Didi Fabian1, Vicktoria Vishnevskia-Dai1,21Department of Ophthalmology, Chaim Sheba Medical Center, Tel Hashomer, Israel; 2Sackler Faculty of Medicine, Tel Aviv University, Tel ...
Kinori M   +5 more
doaj  

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