Results 171 to 180 of about 98,886 (297)

A Unique Case of Compressive Optic Neuropathy From an Internal Carotid Artery Aneurysm. [PDF]

Case Rep Ophthalmol Med
Boyes DS, Bashir K, Skarie JM, Chenevey RE.   +3 more
europepmc   +1 more source

Computed tomographic appearance of melanomas in the equine head: 13 cases [PDF]

A, Albanese, Barnett, Chénier, Cissell, Cotchin, Crijns, Dakin, Dixon, Dyson, Enochs, Fintl, Fukunaga, Ginaldi, Grahn, Holtås, Kalkman, Kato, Lerner, Lucas, Manso-Díaz, McFadyean, Moore, Parizel, Pellegrini, Phillips, Premkumar, Sasaki, Seltenhammer, Textor, Tietje, Tremaine, Uozumi, Valentine, WG, Wörz   +35 more
core   +1 more source

Allogeneic Immune Cell Perfusion Inhibits the Growth of Vascularized 3D In Vitro Tumor Models, Induces Vascular Regression and Desmoplasia, but Promotes Tumor Cell Invasion

Advanced Science, EarlyView.
This study presents a vascularized 3D tumor model to investigate immune–stromal–tumor interactions under allogeneic PBMC perfusion. While immune cells induced tumor shrinkage, they also promoted vascular regression, stromal activation, and cancer cell invasion.
Alexandra Raab, Rasika Daware, Marcelo A. Szymanski de Toledo, Oskar Weber, Dimitris Kapsokalyvas, Twan Lammers, Horst Fischer, Federica De Lorenzi, Fabian Kiessling   +8 more
wiley   +1 more source

Transient orbital apex syndrome with magnetic resonance imaging evidence following sub-Tenon's ropivacaine anesthesia during combined cataract and macular surgery: a case report. [PDF]

BMC Ophthalmol
Cao X, Ge Z, Gong Y.
europepmc   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

A systematic review of stereotactic radiosurgery for pituitary metastases. [PDF]

J Neurooncol
Kite T, Harikumar N, Jaffee S, Knox H, Herbst J, Karlovits S, Yu A, Leonardo J, Wegner RE, Shepard MJ.   +9 more
europepmc   +1 more source

Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira, David Agorku, Andre Rosa, Julia Roosz, Lena Christ, Nicole Anderle, Ajinkya Kulkarni, Abir Hussein, Sana S. Sayedipour, Omar F. Luna, Tobias Legler, Philipp Ströbel, Fernando Albericio, Luis Cruz, Phillipp Beckhove, Peter Loskill, Frauke Alves, M. Andrea Markus, Fernanda Ramos‐Gomes   +18 more
wiley   +1 more source

Evaluation of the Expression of Small Extracellular Vesicle Markers and Their Cargo in Treatment-Naïve Retinoblastoma Tumor Tissues. [PDF]

Transl Vis Sci Technol
Jakati S, Mocherla TR, Pallavi R, Manukonda R, Mishra DK, Vemuganti GK, Kaliki S.   +6 more
europepmc   +1 more source

S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning

Advanced Science, EarlyView.
Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu, Penglei Wang, Gaoyuan Xu, Jitao Lu, Qinke Peng, Danyang Wu, Hequan Sun   +6 more
wiley   +1 more source

Microsurgical resection of olfactory groove meningioma via the pterional transsylvian approach with preservation of the bilateral olfactory nerves. [PDF]

Neurosurg Focus Video
Fidan S, Ibrahim M, Güngör A, Türe U.
europepmc   +1 more source