Results 91 to 100 of about 1,383,877 (253)

Oral administration of diosgenin protects optic nerve degeneration in a mouse model of normal-tension glaucoma

open access: yesPhytomedicine Plus
Introduction: In glaucoma, degeneration of visual pathway spread whole brain area, suggesting that restoring the degenerated axons in the whole visual pathway is crucial for vision recovery.
Chihiro Tohda, Shogo Shibue
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Optic nerve hypoplasia in the fetal alcohol syndrome:a mouse model [PDF]

open access: yes, 1995
Optic nerve hypoplasia is commonly observed in children affected by the fetal alcohol syndrome, and is believed to contribute to their poor visual acuity.
Dhillon, Baljean   +3 more
core  

Optic nerve hemangioblastoma mimicking optic pathway glioma: A case report and literature review

open access: yesRare
Optic nerve hemangioblastomas (ONH) are rare tumors frequently associated with Von Hippel-Lindau (VHL) syndrome. They may mimic optic pathway gliomas (OPG), posing diagnostic and surgical challenges. We report a case of a 36-year-old male presenting with
Ru Jian Jonathan Teoh   +4 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Nutritional optic and peripheral neuropathy: a case report. [PDF]

open access: yes, 2009
INTRODUCTION: The link between nutritional status and either optic or peripheral neuropathies is well established with tobacco, ethanol, deficiencies in thiamine, vitamin A, B12, B3 and B6 and protein-energy malnutrition all being causative.
Nightingale, LM   +3 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The contribution of brain reorganisation to recovery in patients with optic neuritis [PDF]

open access: yes, 2010
In this thesis, the mechanisms of damage and repair in clinically isolated optic neuritis (ON) were investigated in vivo, by combining magnetic resonance imaging (MRI), electrophysiology and optical coherence tomography (OCT).
Jenkins, T.M.
core  

Optic pathway gliomas: a review [PDF]

open access: yes, 2013
Optic pathway gliomas account for 3-5% of all pediatric CNS tumors and represent the most common intrinsic optic nerve tumors. These tumors occur preferentially during the first decade of life and are particularly frequent in children with ...
Tihan, Tarik   +4 more
core   +1 more source

Optic Nerve Sheath Meningioma Masquerading as Optic Neuritis

open access: yesCase Reports in Neurological Medicine, 2016
Optic neuritis is a common presentation of demyelinating disorders such as multiple sclerosis. It typically presents with acute painful monocular vision loss, whereas chronic optic neuropathy can be caused by compressive lesions along the anterior visual
R. Alroughani, R. Behbehani
doaj   +1 more source

Home - About - Disclaimer - Privacy