Results 51 to 60 of about 938,861 (316)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Optical properties of mesoporous photonic crystals, filled with dielectrics, ferroelectrics and piezoelectrics [PDF]
Journal of Advanced Dielectrics, 2017 At present, it is very important to create new types of mirrors, nonlinear light frequency transformers and optical filters with controlled optical properties. In this connection, it is of great interest to study photonic crystals.
V. S. Gorelik, Dongxue Bi, Guang Tao Fei
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Nonlinear optical characterisation of organic chromophores and aspects of molecular aggregation [PDF]
, 2001 The work presented in this thesis describes an investigation into the properties and behaviour of a new class of nonlinear optical organic chromophores.
Hackman, Nancy-Ann
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The optical properties of automatically darkening welding filters based on liquid crystal technology [PDF]
, 1995 This thesis addresses the problem of the poor optical angular properties displayed by the majority of automatically darkening welding filters currently on the market that are based on liquid crystal technology.
Palmer, Stephen John
core
Particle size tuning in silver-polyacrylonitrile nanocomposites
eXPRESS Polymer Letters, 2010 Silver-polyacrylonitrile (Ag-PAN) nanocomposites were in situ synthesized by simultaneous polymerization of acrylonitrile and reduction of silver ions, starting from mixtures of silver nitrate (AgNO3), acrylonitrile (AN), and UV photoinitiator (IN).
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Optical and structural properties of graphene oxide-noble metal bilayers
, 2014 The practical use of graphene and graphene oxide beyond the research laboratories is strictly related to the fine tuning of new methodologies for processing and mass-production purposes.
Simone Silvestrini +17 more
core +1 more source