Results 61 to 70 of about 617,702 (267)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Three Steps, Two Enzymes, One Pot, but a Multitude of Nanocompartments: Combined Cycles of Kinetic Resolutions and Re-racemization with Incompatible Biocatalysts

ACS Omega, 2021
Florian Golombek, Marco Haumann, Matthias S.G. Knoll, Andreas Paul Fröba, Kathrin Castiglione   +4 more
doaj   +1 more source

Optical properties of nuclear matter

Journal of Research of the National Bureau of Standards Section A: Physics and Chemistry, 1976
The index of refraction and absorptive properties are estimated in nuclear matter consisting of protons and neutrons and in nuclear matter charge neutralized by electrons.
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Study on Mechanical Properties, Optical Properties, Cytotoxicity of TiO2-HAP Nanoparticles-Modified PMMA and Photodynamically Assisted Antibacterial Activity Against Candida Albicans in Vitro

International Journal of Nanomedicine
Youbo Liu,1,2 Zhongke Wang,1,2 Xiangrui Liu,1,2 Hongmei Chen,1,2 Ying Huang,1,2 Aodi Li,1,2 Yifan Pu,1,2 Ling Guo1,2 1Department of Oral Prosthodontics, The Affiliated Stomatological Hospital, Southwest Medical University, Luzhou, People’s Republic of ...
Liu Y, Wang Z, Liu X, Chen H, Huang Y, Li A, Pu Y, Guo L   +7 more
doaj  

PROPERTIES OF COMPOSITES BASED ON IRON OXIDE NANOPARTICLES IN LOW DENSITY POLYETHYLENE MATRIX [PDF]

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2012
The results of studies of the dielectric and optical properties of composites based on iron oxides nanoparticles are received. The studies were performed in the temperature range 30 - 100 °C at frequencies of 1 kHz and 1 MHz, and at wavelengths of 600 ...
A.N. Ul’zutuev, N.M. Ushakov
doaj  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source