Results 1 to 10 of about 933,480 (358)

Are ketogenic diets promising for Alzheimer’s disease? A translational review

open access: yesAlzheimer’s Research & Therapy, 2020
Background Brain amyloid deposition and neurofibrillary tangles in Alzheimer’s disease (AD) are associated with complex neuroinflammatory reactions such as microglial activation and cytokine production.
Matthieu Lilamand   +5 more
doaj   +1 more source

The SOS Platform: Designing, Tuning and Statistically Benchmarking Optimisation Algorithms [PDF]

open access: yes, 2020
open access articleWe present Stochastic Optimisation Software (SOS), a Java platform facilitating the algorithmic design process and the evaluation of metaheuristic optimisation algorithms.
Caraffini, Fabio, Iacca, Giovani
core   +1 more source

An Interspecies Molecular and Functional Study of Organic Cation Transporters at the Blood-Brain Barrier: From Rodents to Humans

open access: yesPharmaceutics, 2020
Organic cation transporters (OCTs) participate in the handling of compounds in kidneys and at the synaptic cleft. Their role at the blood-brain barrier (BBB) in brain drug delivery is still unclear.
Catarina Chaves   +11 more
doaj   +1 more source

Associations between circadian misalignment and telomere length in BD: an actigraphy study

open access: yesInternational Journal of Bipolar Disorders, 2022
Background Life expectancy is significantly decreased in bipolar disorder (BD). This is associated with accelerated cellular aging which can be estimated by telomere length (TL). However, specific determinants of shorter TL in BD are under-explored. This
Luana Spano   +5 more
doaj   +1 more source

Exact values for three domination-like problems in circular and infinite grid graphs of small height [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2019
In this paper we study three domination-like problems, namely identifying codes, locating-dominating codes, and locating-total-dominating codes. We are interested in finding the minimum cardinality of such codes in circular and infinite grid graphs of ...
Marwane Bouznif   +3 more
doaj   +1 more source

Methylomic biomarkers of lithium response in bipolar disorder: a clinical utility study

open access: yesInternational Journal of Bipolar Disorders, 2023
Background Response to lithium (Li) is highly variable in bipolar disorders (BD). Despite decades of research, no clinical predictor(s) of response to Li prophylaxis have been consistently identified.
C. Marie-Claire   +6 more
doaj   +1 more source

A Robust Optimisation Strategy for Metal Forming Processes [PDF]

open access: yes, 2007
Robustness, reliability, optimisation and Finite Element simulations are of major importance to improve product\ud quality and reduce costs in the metal forming industry.
Bonte, M.H.A.   +2 more
core   +2 more sources

Structure and Dielectric Properties of V and Y Disorder Doped SrBi2Nb2O9 Ceramics [PDF]

open access: yesArchives of Metallurgy and Materials, 2022
Y and V codoped SrBi 2Nb 2O 9 ceramics, which have been characterized by XRD, FTIR and SEM techniques, were prepared through molten salt using NaCl-KCl medium. Through X-ray diffraction analysis, all prepared samples were matched by undoped SrBi 2Nb 2O 9.
Mohamed Afqir   +4 more
doaj   +1 more source

Optimising load to optimise outcomes [PDF]

open access: yesBritish Journal of Sports Medicine, 2017
The human body is attuned to respond to various forms of mechanical loading and that this is perhaps the primary tool in the repertoire of sports medicine professionals. If exercise is the intervention of choice for a range of conditions, we must appreciate the mechanisms that underpin adaptation so we can refine our prescription and better benefit ...
openaire   +2 more sources

State-of-the-art in aerodynamic shape optimisation methods [PDF]

open access: yes, 2018
Aerodynamic optimisation has become an indispensable component for any aerodynamic design over the past 60 years, with applications to aircraft, cars, trains, bridges, wind turbines, internal pipe flows, and cavities, among others, and is thus relevant ...
Skinner, S.N., Zare-Behtash, H.
core   +1 more source

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