Results 71 to 80 of about 208,937 (301)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Penentuan Ph Optimum Aktivitas Enzim Amilase Dari Pankreas Dan Cairan Usus Ayam Broiler

open access: yes, 2022
Organ digestiva unggas seperti pankreas dan cairan usus berpotensi sebagai sumber enzim hewani. Pada pankreas dan cairan usus (PCU) mengandung berbagai macam enzim, seperti amilase, protease, dan lipase.
Wulandari, Mitha   +2 more
core  

Pengaruh Suhu, pH, dan Salinitas Terhadap Tiga Isolat Bakteri Termo-Proteolitik Asal Sumber Air Panas Pekonina Serta Kondisi Optimum Enzimnya [PDF]

open access: yes, 2021
Telah dilakukan penelitian tentang pengaruh suhu, ph, dan salinitas terhadap tiga isolat bakteri termo-proteolitik asal sumber air panas Pekonina serta kondisi optimum enzimnya yang dilakukan di laboratorium bioteknologi, UPT Sumber Daya Hayati ...
FANINDA RAHMA SARI, Faninda, Rahmasari
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

ANALISA pH OPTIMUM UNTUK PERKEMBANGBIAKAN LACTOBACILLUS BULGARICUS DALAM PROSES FERMENTASI FRUKTOSA PADA SUSU MENJADI ASAM LAKTAT [PDF]

open access: yes, 2010
RINGKASAN Kebutuhan manusia akan produk berbasis bioteknologi seperti fermentasi sekarang ini terus mengalami peningkatan. Dalam proses fermentasi susu peranan Lactobacillus bulgaricus menjadi analisa utama.
Kusuma, Eviana Febi
core  

Purification, characterization and structural determination of chitinases produced by Moniliophthora perniciosa

open access: yesAnais da Academia Brasileira de Ciências, 2012
The enzyme chitinase from Moniliophthora perniciosa the causative agent of the witches' broom disease in Theobroma cacao, was partially purified with ammonium sulfate and filtration by Sephacryl S-200 using sodium phosphate as an extraction buffer ...
Rafaela S. Galante   +8 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

In Silico Modeling of pH-optimum of Protein-Protein Binding

open access: yes, 2010
Protein-protein association is a pH-dependent process and thus the binding affinity depends on the local pH. In vivo the association occurs in a particular cellular compartment, where the individual monomers are supposed to meet and form a complex. Since
Mitra, Rooplekha C   +2 more
core  

N20D/N116E Combined Mutant Downward Shifted the pH Optimum of Bacillus subtilis NADH Oxidase

open access: yes, 2023
Cofactor regeneration is indispensable to avoid the addition of large quantities of cofactor NADH or NAD+ in oxidation-reduction reactions. Water-forming NADH oxidase (Nox) has attracted substantive attention as it can oxidize cytosolic NADH to NAD ...
Xuewei Pan   +6 more
core   +1 more source

Uji Aktivitas Pertumbuhan Enterobacter cloacae Selulolitik Aerob Rumen-1 Isolat Asal Limbah Cairan Rumen Sapi Peranakan Ongole (GROWTH ACTIVITY ASSAY OF CELLULOLYTIC BACTERIA ENTEROBACTER CLOACAE SAR 1 (CELLULOLYTIC AEROB RUMEN 1) ISOLATED FROM ONGOLE CRO

open access: yesJurnal Veteriner, 2016
This study aimedto know the growth activityofcellulolytic bacteria EnterobactercloacaeSAR 1isolatedfrombovinerumen fluidwaste. Isolates that had been cultured were taken as much as 10 mL and thentransferred to100 mL growth medium in Erlenmeyer flask ...
Tri Nurhajati   +2 more
doaj  

Home - About - Disclaimer - Privacy