Results 81 to 90 of about 55,224 (387)
Modeling Interference-Free Neuron Spikes with Optogenetic Stimulation [PDF]
, 2019 This paper predicts the ability to externally control the firing times of a cortical neuron whose behavior follows the Izhikevich neuron model. The Izhikevich neuron model provides an efficient and biologically plausible method to track a cortical neuron'
Eckford, Andrew W. +3 more
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Optogenetics: Emerging strategies for neuropathic pain treatment
Frontiers in Neurology, 2022 Neuropathic pain (NP) is a chronic health condition that presents a significant burden on patients, society, and even healthcare systems. However, in recent years, an emerging field in the treatment of neuropathic pain – optogenetic technology has dawned,
Siyu Li +3 more
doaj +1 more source
The search for novel analgesics: re-examining spinal cord circuits with new tools [PDF]
, 2014 In this perspective, we propose the absence of detailed information regarding spinal cord circuits that process sensory information remains a major barrier to advancing analgesia.
Brett A Graham +8 more
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Keeping track of worm trackers [PDF]
, 2012 C. elegans is used extensively as a model system in the neurosciences due to its well defined nervous system. However, the seeming simplicity of this nervous system in anatomical structure and neuronal connectivity, at least compared to higher animals ...
Gottschalk, Alexander +3 more
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Optogenetic Approaches in Neuroscience [PDF]
Current Biology, 2010 The recently introduced term 'optogenetics' describes a variety of techniques for expressing genes in nerve cells that render them responsive to light. This approach makes use of light-sensitive channel proteins that can be used to manipulate neuronal function.
Oliver M. Schlüter +2 more
openaire +3 more sources
Optogenetics Therapy of Human Cancers
Zhongliu Fangzhi Yanjiu, 2018 The optogenetics approach uses a combination of genetic and optical methods to control the functions in specific cells of biological tissues. Since the control of neuronal activity by irradiating channelrhodopsin-2 with blue light was reported in 2005 ...
ZHANG Baihong, YUE Hongyun
doaj +1 more source
, 2012 The use of optogenetics, the technology that combines genetic and optical methods to monitor and control the activity of specific cell populations, is now widely adopted in neuroscience. The development of optogenetic tools, such as natural photosensitive ion channels and pumps or calcium- and voltage-sensitive proteins, has been growing tremendously ...
Oron, Dan +3 more
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Optogenetic Regeneration [PDF]
Science, 2014 Applying tools from optogenetics with ideas from regenerative medicine may herald a new era of translational optogenetics. [Also see Report by Bryson et al. ]
Scott L. Delp, Shrivats Mohan Iyer
openaire +3 more sources
Exploring adult hippocampal neurogenesis using optogenetics [PDF]
, 2018 In the 1980s, it was widely accepted that new neurons are continuously generated in the dentate gyrus of the mammalian hippocampus. Since its acceptance, researchers have employed various techniques and behavioral paradigms to study the proliferation ...
Pinardo, Heinrich
core
Roadmap on semiconductor-cell biointerfaces. [PDF]
, 2018 This roadmap outlines the role semiconductor-based materials play in understanding the complex biophysical dynamics at multiple length scales, as well as the design and implementation of next-generation electronic, optoelectronic, and mechanical devices ...
Anikeeva, Polina +24 more
core +1 more source