Results 71 to 80 of about 2,522,619 (179)

Detection of Genes Related to Linezolid Resistance (poxtA, cfr, and optrA) in Clinical Isolates of Enterococcus spp. from Humans: A First Report from Iran

open access: yesAdvanced Biomedical Research, 2023
Background: Enterococci may develop resistance to linezolid through chromosomal mutations that involve specific linezolid resistance genes, such as cfr, optrA, and poxtA.
Majid Torabi   +2 more
doaj   +1 more source

Identification of Outer Membrane Vesicles as a New Vehicle Mediating Antibiotic Resistance Gene Transfer in Campylobacter

open access: yesJournal of Extracellular Vesicles, Volume 14, Issue 11, November 2025.
ABSTRACT The emergence and worldwide dissemination of antibiotic resistance genes (ARGs) compromise antibiotic therapy and are a major public health crisis. Horizontal gene transfer (HGT) plays a major role in the spread of ARGs among bacterial pathogens.
Mengyu Zhao   +8 more
wiley   +1 more source

Emergence of optrA-mediated linezolid resistance in clinical isolates of Enterococcus faecalis from Argentina [PDF]

open access: yes, 2023
: Objectives: The aim of this study was to characterize the first 14 optrA-carrying linezolid resistant E. faecalis clinical isolates recovered in seven Argentinian hospitals between 2016 and 2021.
Faccone, Diego Francisco   +12 more
core   +1 more source

Antibiotic Resistance: A Genetic and Physiological Perspective

open access: yesMedComm, Volume 6, Issue 11, November 2025.
The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy   +9 more
wiley   +1 more source

Identification of plasmids co-carrying cfr(D)/optrA and cfr(D2)/poxtA linezolid resistance genes in two Enterococcus avium isolates from swine brain

open access: yes, 2023
Oxazolidinones are critically important antibiotics to treat human infections caused by multidrug-resistant bacteria, therefore the occurrence of linezolid-resistant enterococci from food-producing animals poses a serious risk to human health.
Aquilanti, Lucia   +10 more
core   +1 more source

Spatio‐temporal characteristics of the gastrointestinal resistome in a cow‐to‐calf model and its environmental dissemination in a dairy production system

open access: yesiMeta, Volume 4, Issue 4, August 2025.
This study revealed spatio‐temporal characteristics of gastrointestinal resistome in a cow‐to‐calf model and the pattern of their spread to the environment and offspring in the dairy production system. The gastrointestinal tract of dairy cows is a natural reservoir of resistomes and distinguished by gut sites and regions.
Shuai Liu   +19 more
wiley   +1 more source

Comparative Genomic and Phylogenetic Analysis of Salmonella enterica Isolated From Donkey

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Salmonella is one of the most prevalent foodborne and zoonotic pathogens threatening global public health and food safety. Salmonella enterica subspecies enterica serovar Abortusequi (S. Abortusequi) is frequently reported as the etiological agent of equine abortion, septicemia, and polyarthritis.
Yuhui Tian   +7 more
wiley   +1 more source

Streptococcus suis Serotype 14: A Nonnegligible Zoonotic Population

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Streptococcus suis is an important zoonotic pathogen that can cause severe infections in both humans and pigs. The prevalence of S. suis serotype 14 in sporadic cases in China has been gradually increasing during recent years. However, the current understanding of S. suis serotype 14 is limited.
Liangliang Wu   +8 more
wiley   +1 more source

Detection of Oxazolidinone Resistance Genes and Characterization of Genetic Environments in Enterococci of Swine Origin, Italy

open access: yesMicroorganisms, 2020
One hundred forty-five florfenicol-resistant enterococci, isolated from swine fecal samples collected from 76 pig farms, were investigated for the presence of optrA, cfr, and poxtA genes by PCR.
Simona Fioriti   +13 more
doaj   +1 more source

Genetic Characterization of a Linezolid‐ and Penicillin‐Resistant Enterococcus hirae Isolate Co‐Harboring poxtA and pbp5fm

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Linezolid and penicillin are critical for treating multidrug resistant (MDR) Gram‐positive infections, but the emergence of resistance to both seriously threatens public health. Here, we first report the cocarrying poxtA (oxazolidinone resistance) and pbp5fm (β‐lactam resistance) genes by the plasmid in a strain of Enterococcus hirae HDC14‐2 derived ...
Jinhu Huang   +7 more
wiley   +1 more source

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