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GENERAL ANALGESIA BY ORAL ADMINISTRATION [PDF]

open access: greenBMJ, 1918
This report is in the nature of a preliminary communication based on animal experiments and a sufficient number of clinical cases to support the conclusions of the animal work. It will be seen that general analgesia in which there is loss of sensation, with or without loss of consciousness, can be established for otherwise painful dressings and for ...
J. T. Gwathmey, Howard T. Karsner
openalex   +5 more sources

Rose Bengal–Chitosan Nanocomposites for Oral Administration [PDF]

open access: yesNanomaterials
Rose Bengal (RB) holds promise for therapeutic applications in the gastrointestinal (GI) tract but faces significant limitations due to poor bioavailability and stability in the GI environment.
Sara Demartis   +7 more
doaj   +2 more sources

Oral administration microrobots for drug delivery. [PDF]

open access: yesBioact Mater
Oral administration is the most simple, noninvasive, convenient treatment. With the increasing demands on the targeted drug delivery, the traditional oral treatment now is facing some challenges: 1) biologics how to implement the oral treatment and ensure the bioavailability is not lower than the subcutaneous injections; 2) How to achieve targeted ...
Ren A   +9 more
europepmc   +4 more sources

Oral administration of glycyrrhizic acid with intramuscular injection of foot-and-mouth disease vaccine enhances the adaptive immune system [PDF]

open access: yesFrontiers in Microbiology
BackgroundCommercial foot-and-mouth disease (FMD) vaccines have several drawbacks, including a short duration of the immune response after vaccination and local adverse reactions at the vaccination site. Therefore, we developed a new vaccination strategy
Seokwon Shin   +6 more
doaj   +2 more sources

Pharmacokinetics of cannabidiol following single oral and oral transmucosal administration in dogs

open access: yesFrontiers in Veterinary Science, 2023
IntroductionIn the last few years, different formulations containing cannabidiol (CBD) were tested with regard to its efficacy on chronic pain, refractory epilepsy, anxiety, aggressive behavior and atopic dermatitis in dogs. CBD is generally administered
Giorgia della Rocca   +11 more
doaj   +1 more source

Oral administration of Blautia wexlerae ameliorates obesity and type 2 diabetes via metabolic remodeling of the gut microbiota

open access: yesNature Communications, 2022
The gut microbiome is an important determinant in various diseases. Here we perform a cross-sectional study of Japanese adults and identify the Blautia genus, especially B.
Koji Hosomi   +26 more
semanticscholar   +1 more source

Probiotic Gastrointestinal Transit and Colonization After Oral Administration: A Long Journey

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Orally administered probiotics encounter various challenges on their journey through the mouth, stomach, intestine and colon. The health benefits of probiotics are diminished mainly due to the substantial reduction of viable probiotic bacteria under the ...
Shengyi Han   +11 more
semanticscholar   +1 more source

Are ministerial recommendations sufficient to avoid bisphosphonate related osteonecrosis of the jaw? A case report

open access: yesAnnali di Stomatologia, 2021
Bisphosphonate related osteonecrosis of the jaw (BRONJ) can occur in patients affected by malignancy associated hypercalcemia, bone metastases of solid tumors or multiple myeloma intaking amino-bisphosphonates or other bone resorption inhibitors.
A. Massaria   +3 more
doaj   +1 more source

Sublingual Vaccination with Live Influenza Virus Induces Better Protection Than Oral Immunization in Mice

open access: yesLife, 2022
Both sublingual (SL) and oral vaccine administration modalities are convenient, easy, and safe. Here, we have investigated the differences in vaccine efficacy that are induced by oral and sublingual immunization with live influenza virus (A/Hong Kong/1 ...
Jie Mao   +5 more
doaj   +1 more source

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