Results 1 to 10 of about 808,923 (313)

Rose Bengal–Chitosan Nanocomposites for Oral Administration [PDF]

Nanomaterials
Rose Bengal (RB) holds promise for therapeutic applications in the gastrointestinal (GI) tract but faces significant limitations due to poor bioavailability and stability in the GI environment.
Sara Demartis, Camila J. Picco, Octavio E. Fandiño, Eneko Larrañeta, Ryan F. Donnelly, Paolo Giunchedi, Giovanna Rassu, Elisabetta Gavini   +7 more
doaj   +2 more sources

Valbenazine Sprinkle: An Alternative Formulation of Valbenazine for Oral Administration in Patients With Dysphagia [PDF]

Clinical and Translational Science
Valbenazine is a vesicular monoamine transporter 2 (VMAT2) inhibitor approved for the treatment of tardive dyskinesia and Huntington's chorea. Dysphagia, pill aversion, and fear of swallowing are common in patients with these conditions.
Nagdeep Giri, Roland Jimenez, Linda Rees, Alexander Mar, Ali Bristow, Mello Hebert, Jessica Maynard‐Scott, Hui Zhang, Satjit Brar   +8 more
doaj   +2 more sources

Intestinal mucosal immune responses induced by oral administration of chitosan nanoparticles encapsulating the PEDV S1 protein [PDF]

Veterinary Research
Porcine epidemic diarrhea (PED), a highly contagious intestinal disease caused by PEDV, threatens newborn piglets and causes enormous losses in the swine industry. Intestinal mucosal immunity is vital for defense against PEDV.
Kai Su, Jing Ren, Yanan Zhang, Chen Yuan, Yawen Wang, Liu Yang, Lizhi Fu, Tingli Fan, Qinye Song   +8 more
doaj   +2 more sources

Pharmacokinetics of cannabidiol following single oral and oral transmucosal administration in dogs

Frontiers in Veterinary Science, 2023
IntroductionIn the last few years, different formulations containing cannabidiol (CBD) were tested with regard to its efficacy on chronic pain, refractory epilepsy, anxiety, aggressive behavior and atopic dermatitis in dogs. CBD is generally administered
Giorgia della Rocca, Giorgia della Rocca, Fabiola Paoletti, Maria Beatrice Conti, Maria Beatrice Conti, Roberta Galarini, Elisabetta Chiaradia, Monica Sforna, Cecilia Dall'Aglio, Angela Polisca, Alessandra Di Salvo, Alessandra Di Salvo   +11 more
doaj   +1 more source

PAK1 inhibitor NVS‐PAK1‐1 inhibits degeneration of synaptic spines in cultured neurons exposed to amyloid or tau and in 5XFAD mice following oral administration [PDF]

Alzheimers Dement
Longo F.
europepmc   +3 more sources

Are ministerial recommendations sufficient to avoid bisphosphonate related osteonecrosis of the jaw? A case report

Annali di Stomatologia, 2021
Bisphosphonate related osteonecrosis of the jaw (BRONJ) can occur in patients affected by malignancy associated hypercalcemia, bone metastases of solid tumors or multiple myeloma intaking amino-bisphosphonates or other bone resorption inhibitors.
A. Massaria, M.V. Bartolucci, R. Baldi, M. Messi   +3 more
doaj   +1 more source

Sublingual Vaccination with Live Influenza Virus Induces Better Protection Than Oral Immunization in Mice

Life, 2022
Both sublingual (SL) and oral vaccine administration modalities are convenient, easy, and safe. Here, we have investigated the differences in vaccine efficacy that are induced by oral and sublingual immunization with live influenza virus (A/Hong Kong/1 ...
Jie Mao, Gi-Deok Eom, Keon-Woong Yoon, Hae-Ji Kang, Ki-Back Chu, Fu-Shi Quan   +5 more
doaj   +1 more source

The relationship between children’s oral health behaviours and oral health-related quality of life: a cross-sectional study

BMC Oral Health, 2023
Background Understanding oral health behaviour s and their impact on Oral Health-Related Quality of Life (OHRQoL) may serve as an instrument to articulate the conventional oral health policy framework, thereby ameliorating the overall health of young ...
Hanan Boodai, Mohamed ElSalhy, Aishah Alsumait, Jitendra Ariga, Marwan Al-Sharbati   +4 more
doaj   +1 more source

Dose–Response Study of Microcystin Congeners MCLA, MCLR, MCLY, MCRR, and MCYR Administered Orally to Mice

Toxins, 2021
Microcystins are common freshwater cyanobacterial toxins that affect liver function. The toxicities of five microcystin congeners (microcystin-LA (MCLA), MCLR, MCLY, MCRR, and MCYR) commonly observed in harmful algal blooms (HABs) were evaluated in BALB ...
Neil Chernoff, Donna Hill, Johnsie Lang, Judith Schmid, Amy Farthing, Hwa Huang   +5 more
doaj   +1 more source

Cocrystallization of Gefitinib Potentiate Single-Dose Oral Administration for Lung Tumor Eradication via Unbalancing the DNA Damage/Repair

Pharmaceutics, 2023
Gefitinib (GEF) is a clinical medication for the treatment of lung cancer targeting the epidermal growth factor receptor (EGFR). However, its efficacy is remarkably limited by low solubility and dissolution rates.
Muhammad Inam, Yi Yang, Jialin Hu, Jiena Zheng, Wenxia Deng, You Zhou, Jialong Qi, Chuanshan Xu, Guihong Chai, Yuanye Dang, Wenjie Chen   +10 more
doaj   +1 more source