Results 171 to 180 of about 1,639,084 (252)

KIT Somatic Mutations and Immunohistochemical Expression in Canine Oral Melanoma. [PDF]

Animals (Basel), 2020
Brocca G, Poncina B, Sammarco A, Cavicchioli L, Castagnaro M.   +4 more
europepmc   +1 more source

Effects of Green Tea Supplementation on Chemoprevention at Different Stages of Carcinogenesis: A Systematic Review

Phytotherapy Research, EarlyView.
ABSTRACT Green tea catechins have chemopreventive potential; however, the clinical evidence remains inconsistent. This review evaluated the effects of supplementation with green tea derivatives on chemoprevention at different stages of carcinogenesis. PubMed, Embase, Web of Science, Scopus, the Cochrane Library, CINAHL, and Google Scholar were searched
Thaís Moreira Machado, Mariene Garcia Gomes, Érika Yuri Hirose Murahara, Ana Lúcia Chalhoub Chediac Rodrigues, Ariane Nadolskis Severine, Thais Giovaninni Roberto, Sinara Laurini Rossato   +6 more
wiley   +1 more source

Natural Products Exhibit Therapeutic Potential in Treating Rheumatoid Arthritis by Targeting the PI3K/Akt Signaling Pathway

Phytotherapy Research, EarlyView.
This review summarizes how natural products, mainly including flavonoids, terpenoids, alkaloids, and polyphenols alleviate RA via PI3K/Akt pathway, regulating inflammation, proliferation, apoptosis, angiogenesis, and osteoclast differentiation. The figure was created by Figdraw (https://www.figdraw.com/#/).
Haishuo Ren, Yige Wang, Wenjing Ma, Omachi Daniel Ogaji, Shujing Chen, Kunze Du, Xuemi Zhang, Bo Xu, Shanxing Zhai, Shiming Fang, Yanxu Chang   +10 more
wiley   +1 more source

SOX Family Members Expression in Canine Oral Melanoma: Role of the SOX3 in Tumor Aggressiveness. [PDF]

Vet Sci
Costa RF, Carvalho BA, Lima BM, Veloso ES, Nakagaki KYR, Gonçalves INN, Del Puerto HL, Ferreira E.   +7 more
europepmc   +1 more source

Plant‐Derived Extracellular Vesicles: Biogenesis, Function, and Application in Cancer Immunotherapy

Phytotherapy Research, EarlyView.
This illustration shows the biogenesis pathways of edible and medicinal plant‐derived extracellular vesicles (PDEVs) and their therapeutic effects following uptake in the human body, highlighting their potential for application in cancer immunotherapy. ABSTRACT Plant‐derived extracellular vesicles (PDEVs) are nanoscale, lipid bilayer‐enclosed vesicles ...
Guosheng Li, Mengyu Li, Shujing Liu, Yuan Wei, Chen Wang   +4 more
wiley   +1 more source

Pilot Transcriptomic Profiling of Canine Oral Melanoma Reveals Conserved Oncogenic Pathways and Uncharacterized Molecular Signatures. [PDF]

Cancers (Basel)
Pérez-Santana CG, Rodríguez-Esparragón F, Cazorla-Rivero SE, Jiménez-Alonso AA, Clavo B, González-Martín JM, Cánovas-Molina Á, Bartolomé C, Estupiñán L, Rodríguez Grau-Bassas E.   +9 more
europepmc   +1 more source

A New Clinical Paradigm: Stratified Gut Microbiota Interventions to Enhance Efficacy and Attenuate Toxicity of Cancer Immunotherapy

Microbiota Medicine Research, EarlyView.
Liang Zhang, Xinyu Du, Lijuan Sun, Ziyi Shi, Yongzhan Nie   +4 more
wiley   +1 more source

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Transcriptome analysis of dog oral melanoma and its oncogenic analogy with human melanoma. [PDF]

Oncol Rep, 2020
Rahman MM, Lai YC, Husna AA, Chen HW, Tanaka Y, Kawaguchi H, Hatai H, Miyoshi N, Nakagawa T, Fukushima R, Miura N.   +10 more
europepmc   +1 more source