Results 181 to 190 of about 1,639,084 (252)

Catch me if you can! Novel immune escape mechanisms in melanoma metastases of the brai

, 2018
The immune system is one of the key modulator directing tumor growth and progression, but also therapy responsiveness. Recent reports clearly idicate that drug activity in the brain is not only directed by the drug susceptibility to penetrate the blood ...
Helfrich, I.*, Herz, J., Singer, B., Sure, U., Schadendorf, D., Hinze, D., Kammerer, Robert, Felsberg, J., Herrera-Rios, D., Schmitt, V., Reifenberger, G., Hölzel, M., Pierscianek, D.   +12 more
core  

Advances in research on layered double hydroxides for biomedical applications

Smart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang, Zhiping Zhang, Zhao Wang, Hao Zhang, Yen Leng Pak, Yingying Jing, Yurong Guo, Fang Li, Xiao Wang, Quanxiang Han, Lei Yu, Xuejiao Li, Xing Gao, Jibin Song   +13 more
wiley   +1 more source

Hypoxia-related Y RNA fragments as a novel potential biomarker for distinguishing metastatic oral melanoma from non-metastatic oral melanoma in dogs. [PDF]

Vet Q
Hasan MN, Rahman MM, Husna AA, Kato D, Nakagawa T, Arif M, Miura N.   +6 more
europepmc   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

PD-L1, PD-1, and CTLA-4 mRNA In Situ Expression by Canine Oral Melanoma Cells and Immune Cells of the Tumour Microenvironment. [PDF]

Vet Comp Oncol
Foiani G, Melchiotti E, Capello K, Porcellato I, Brachelente C, Iussich S, Giacobino D, Morello E, Martano M, Buracco P, Vascellari M.   +10 more
europepmc   +1 more source

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

VIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore, Beatrice Pellegrini, Antonia Mancuso, Maria Chiara Cristiano, Salvatore Panza, Donatella Paolino   +5 more
wiley   +1 more source

Outcomes in Orbit‐Sparing Versus Orbit‐Sacrificing Surgery for Sinonasal Malignancies With Orbital Involvement: A Systematic Review and Meta‐Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Sinonasal malignancies with orbital involvement may be managed with orbit‐sacrificing or orbit‐preserving surgical approaches, with a recent shift towards orbital preservation to reduce postoperative morbidity while maintaining oncological success.
Claire Jing‐Wen Tan, Brian Sheng Yep Yeo, Manish Warrier, Jun He Chan, Lu Hui Png, Shuhui Xu, Kimberley LiQin Kiong, Edward C. Kuan, Tze Choong Charn, Neville Wei Yang Teo   +9 more
wiley   +1 more source

Melanoma primario de mucosa nasosinusal y bucal: Revisión narrativa

Ciencia, Tecnología y Salud
Los melanomas primarios de mucosa nasosinusal y bucal (MPMNSB) son tumores agresivos e infrecuentes; muestran un comportamiento biológico diferente al de su contraparte cutánea.
Bryan Manolo Orellana Higueros, Elisa Hernández   +1 more
doaj  

Upregulation and functional roles of miR-450b in canine oral melanoma. [PDF]

Noncoding RNA Res
Hasan MN, Rahman MM, Husna AA, Arif M, Jasineviciute I, Kato D, Nakagawa T, Miura N.   +7 more
europepmc   +1 more source

Biomarkers Predictive of Immunotherapy Efficacy in Head and Neck Squamous Cell Carcinoma: Current Insights and Future Perspectives

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT With the approval of immunotherapies by regulatory bodies, head and neck squamous cell carcinoma (HNSCC) treatment has been revolutionized, and anti‐programmed cell death‐1 (anti‐PD‐1) agents are now the standard for platinum‐resistant recurrent/metastatic HNSCC.
Xiao‐Tong Yan, Zhao‐Hong An, Chang‐Ming An   +2 more
wiley   +1 more source