Results 51 to 60 of about 2,471,598 (337)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Crack growth measured on flat and curved surfaces at cryogenic temperatures [PDF]

open access: yes, 1967
Multiple element continuity gage measures plane stress crack growth plus surface crack growth under plane strain conditions.
Orange, T. W., Sullivan, T. L.
core   +1 more source

Adsorption of methyl orange on ZnO supported by seawater-modified red mud [PDF]

open access: diamond, 2022
Chun-Lei Qiao   +5 more
openalex   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Effects of Various Steam Explosions on the Efficiency, Yield, and Loss in a Hydraulic Press Extractor of Fruit Juice

open access: yesJurnal Keteknikan Pertanian Tropis dan Biosistem
High post-harvest losses occur as a result of the fruits rapid decline in quality after harvest. Using a steam exploded simple juicer is one approach to make up for this loss.
Oluwafemi Babatunde Oduntan   +3 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Des ambitions raisonnables et raisonnées. Accéder à l’enseignement supérieur par les IUT et les STS

open access: yesCahiers de la Recherche sur l'Education et les Savoirs, 2018
A large number of students enter STS or IUT after the baccalaureate by default, either because they have given up their candidacy in another form of education they prefer because of their low school level, or they were not admitted.
Sophie Orange
doaj   +1 more source

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