Results 151 to 160 of about 87,713 (271)
Magnetic Resonance in Medicine, Volume 95, Issue 6, Page 3270-3283, June 2026.ABSTRACT Purpose To apply the Magnetization Transfer Indirect Spin Labeling (MISL) MRI technique for quantifying tissue‐CSF water exchange in the human brain, and to investigate its utility in (1) evaluating tissue‐CSF water exchange within perivascular spaces (PVS), and (2) characterizing altered water exchange dynamics in pathologic conditions ...
Yihan Wu +8 more
wiley +1 more source
Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.The histamine H3 receptor antagonist/inverse agonist pitolisant did not affect temporal prediction and spatial switching. ABSTRACT Histamine receptors contribute to a wide range of brain functions, including arousal, motivation, attention, and memory, but their causal involvement in switching behavior remains insufficiently understood.
Shohei Kaneko +3 more
wiley +1 more source
Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.The odds ratios and corresponding 95% confidence intervals for suicide death by 5‐HTTLPR S allele, in main and subgroup analyses. Statistical significance is indicated. ABSTRACT Introduction More than 720 000 individuals die by suicide annually worldwide, making it a major public health concern and a leading cause of death among young people ...
Shohei Okada +11 more
wiley +1 more source
Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.This study examined the association between attention‐deficit/hyperactivity disorder (ADHD) traits and gray matter volume (GMV) in 534 healthy young adults. Higher Hyperactivity/Restlessness scores were associated with greater GMV in the right dorsolateral prefrontal cortex (DLPFC), a region implicated in executive control and behavioral regulation. No
Haruka Asaoka +4 more
wiley +1 more source
Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.ABSTRACT Cognitive impairments are important therapeutic targets in epilepsy medication; however, effective pharmacological treatments for epilepsy patients with comorbid cognitive impairment have not been established. Effects of chronic administration of MK‐801 (noncompetitive NMDA receptor inhibitor), memantine (low‐affinity extrasynaptic‐NMDA ...
Motohiro Okada +3 more
wiley +1 more source
Addiction, Volume 121, Issue 6, Page 1541-1556, June 2026.Abstract Background and aims Recreational ketamine use has increased globally and is associated with psychiatric and cognitive concerns. The hippocampus in preclinical models shows damage and working‐memory disruption with repeated dosing. However, whether specific hippocampal subregions may differ in people with chronic ketamine use remains unclear ...
Yi‐Hsuan Liu +8 more
wiley +1 more source
Australasian Journal on Ageing, Volume 45, Issue 2, June 2026.ABSTRACT Objective With the trend of population ageing, cognitive frailty in older adults is an increasingly pressing public health issue. Identifying early‐stage risk factors has become a key priority for researchers with the goal of preventing disability.
Li‐Jun Chen +6 more
wiley +1 more source
Abnormal amyloid PET usually represents intermediate/high Alzheimer's disease neuropathologic change
Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.Abstract INTRODUCTION Alzheimer's disease neuropathologic change (ADNC) classification identifies not/low and intermediate/high levels of neuropathology. Our goal was to assess how frequently a positive amyloid positron emission tomography (PET) scan indicates not/low ADNC and whether this autopsy finding can occur >10 years after a positive amyloid ...
Brian J. Burkett +16 more
wiley +1 more source
Tau Pathology in Alzheimer's Disease Uniquely Affects Sulcal Depths
Annals of Neurology, Volume 99, Issue 5, Page 1343-1353, May 2026.Objective Though it is widely known that tau deposition affects brain structure, the precise localization of these effects is poorly understood, especially in relation to gyral and sulcal anatomy. We investigated whether tau pathology in Alzheimer's disease (AD) preferentially affects sulci, and particularly sulcal depths.
Samira A. Maboudian +10 more
wiley +1 more source
Functional Connectivity During Social Reward Processing in Autistic and Neurotypical Adolescents
Brain and Behavior, Volume 16, Issue 5, May 2026.Heightened task‐evoked functional connectivity was observed in autistic youth between the amygdala and the posterior superior temporal sulcus (pSTS), core regions of the social reward circuitry, on receipt of a social‐interactive reward. The strength of connectivity was negatively correlated with enjoyment of social interaction.
Hua Xie +6 more
wiley +1 more source