Results 121 to 130 of about 7,628 (191)

Expression of SARS-CoV-2-ORF3a protein induces cardiomyocyte damage

Biophysical Journal, 2022
Polina, Iuliia A., Guo, Yugene, Cypress, Michael W., Tolkacheva, Elena G., Sook Jhun, Bong, O-Uchi, Jin   +5 more
openaire   +2 more sources

Molecular characterization and phylogenetic analysis of transmissible gastroenteritis virus HX strain isolated from China [PDF]

, 2015

core   +1 more source

CD81 fusion alters SARS-CoV-2 Spike trafficking. [PDF]

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic caused the biggest public health crises in recent history. Many expect future coronavirus introductions into the human population.
Arias, Gabriel F, Chambers, Meredith G, Cone, Allaura S, Dittmer, Dirk P, Eason, Anthony B, Griffith, Jack D, Landis, Justin T, McNamara, Ryan P, Shifflett, Kyle W, Willcox, Smaranda, Yuan, Runjie, Zhou, Yijun   +11 more
core   +2 more sources

Author Correction: Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs [PDF]

Nature Structural & Molecular Biology, 2021
David M. Kern, Ben Sorum, Sonali S. Mali, Christopher M. Hoel, Savitha Sridharan, Jonathan P. Remis, Daniel B. Toso, Abhay Kotecha, Diana M. Bautista, Stephen G. Brohawn   +9 more
openaire   +1 more source

How many SARS-CoV-2 “viroporins” are really ion channels? [PDF]

, 2022
Abbott G. W., Aleksandrov A., Garcia D. C., Gentzsch M., Grant S., Harrison N. L., Hartel A., Lester H. A., Moroni A., Nichols C. G., Shepard K., Thiel G., Yazawa M.   +12 more
core   +1 more source

Reprogramming of lipid metabolism by ORF3a-induced microlipophagy enhances biogenesis of SARS-CoV-2 replication organelle. [PDF]

PLoS Pathog
Li Z, Hui X, Zheng M, He Z, Huai W, Ding B, Jin M, Qin Y, Chen M.   +8 more
europepmc   +1 more source

Distinct mutational landscapes and phylogenomic insights of the SARS-CoV-2 delta variant in Pakistan and India: Regional evolution, novel mutations, and epidemiological implications. [PDF]

PLoS One
Fiaz N, Basheer A, Zahoor I, Naveed S, Yaqub T.   +4 more
europepmc   +1 more source

Autophagy induction by SARS-CoV-2 ORF3a depends on JNK signaling

SARS-CoV-2 open reading frame 3a (ORF3a) is a non-structural and an accessory protein that is involved in the pathogenesis of COVID-19. ORF3a manipulates with autophagosomes and lysosomal degradation to support SARS-CoV-2 replication and egress. The signaling pathways by which ORF3a regulates autophagy are not fully understood.
Mandić, Miloš, Vučićević, Ljubica, Misirkić Marjanović, Maja, Bošnjak, Mihajlo, Stevanović, Danijela, Paunović, Verica, Kosić, Milica, Trajković, Vladimir   +7 more
openaire   +1 more source

Cleaved SREBP-2 C-terminal fragment noncanonically drives interleukin-1 receptor-associated kinase 1-dependent apoptosis. [PDF]

Signal Transduct Target Ther
Yeon M, Kim WK, Shin HB, Lee YB, Rhee HW, Seo YK.   +5 more
europepmc   +1 more source

Hidden players of COVID-19: the evolving roles of SARS-CoV-2 accessory proteins. [PDF]

Front Immunol
Padilla-Blanco M, García-García T, Grigas J, López-Ayllón BD, Garrido JJ, Oliva MA, Montoya M.   +6 more
europepmc   +1 more source