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The SARS coronavirus accessory protein ORF3a rescues potassium conductance in yeast
microPublication BiologyORF3a is an accessory protein expressed by all human pathogen coronaviruses and is the only accessory protein that strongly affects viral fitness. Its deletion reduces severity in both alpha- and beta-coronaviruses, demonstrating a conserved function ...
Joel C. Rosenbaum, Anne E. Carlson
semanticscholar +1 more source
Myelin basic protein antagonizes the SARS-CoV-2 protein ORF3a-induced autophagy inhibition.
BiochimieInhibition of autophagy is one of the hallmarks of the SARS-CoV-2 infection. Recently it was reported that SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes via interaction with VPS39 thus preventing binding of homotypic fusion ...
G. A. Saratov +2 more
semanticscholar +1 more source
SARS-Cov-2 ORF3a: Mutability and function
International Journal of Biological Macromolecules, 2021Martina Bianchi +2 more
exaly
Pathogenic perspective of missense mutations of ORF3a protein of SARS-CoV-2
Virus Research, 2021Sk Sarif Hassan +2 more
exaly
SARS-CoV-2 accessory proteins ORF3a and ORF6 alter the miRNome of human lung epithelial cells
Molecular Biology ReportsApoorva +3 more
semanticscholar +1 more source
Molecular conservation and differential mutation on ORF3a gene in Indian SARS-CoV2 genomes
Genomics, 2020Sk Sarif Hassan +2 more
exaly