Results 111 to 120 of about 6,314 (165)

Unmasking SARS-CoV-2 ORF3a; a hidden trigger of immune overdrive in COVID-19

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), became a global health crisis in 2020, leading to widespread severe cases.
Ezeanyaegbu, Calvin Nnaemeka
core   +1 more source

Exosomal ORF3a mediates lung-liver axis to dysregulate hepatic lipid metabolism in mild COVID-19. [PDF]

Cell Discov
Qu Y, Zhou J, Wang X, Dong S, Li J, Qiu L, Bian L, Yuan W, Xie Q, Qu J, Zhao Z, Wu X, Liang Q.   +12 more
europepmc   +1 more source

Correlation of the cumulative number of symptoms of COVID-19 patients and cycle threshold value the Open Reading Frame 3a (ORF3a) and N gene.

Correlation of the cumulative number of symptoms of COVID-19 patients and cycle threshold value the Open Reading Frame 3a (ORF3a) and N gene.
Issabella Asamoah (17941272), Allen Steele-Dadzie (17941281), Kwamena W. C. Sagoe (17334446), Albert Turkson (17941287), Quaneeta Mohktar (17563371), Bright Adu (133241), Atta Senior Kuffour (17941284), Kantanka Addo-Osafo (3498869), Priscilla Vandyck-Sey (17941278), Yaw A. Afrane (8491401), Mildred Adusei-Poku (17941275), Ivy Asantewaa Asante (13783364)   +11 more
core   +1 more source

Genomic Characterization of SARS-CoV-2 NB.1.8.1 and PQ.2 from the Infants and Young Children with Gastrointestinal Symptoms. [PDF]

Infect Drug Resist
Zhang X, Guo X.
europepmc   +1 more source

SARS-CoV-2 ORF3a suppresses host antiviral interferon responses by promoting STUB1-mediated PTEN proteasomal degradation. [PDF]

J Virol
Fan L, Gao X, Feng W, Huang Q, Wei X, Yang C, Wu Y, Shen X, Zhao J, Zhou Y, Zhang Z.   +10 more
europepmc   +1 more source

BST-2 inhibits SARS-CoV-2 egress at intracellular membranes and is neutralized by ORF7a. [PDF]

Sci Rep
Smith A, Dong X.
europepmc   +1 more source

Targeting SARS-CoV-2 Structural and Accessory Proteins: Emerging Opportunities for Small-Molecule Coronavirus Antivirals. [PDF]

Pharmaceutics
Porta EOJ, AlKharboush DF, Jackson L, Pang F, Darin A, Louka J, Shi X, Wells G, Kozielski F.   +8 more
europepmc   +1 more source

Structural and Computational Insights into the Attenuated Innate Immune Recognition of the SARS-CoV-2 N15 Lineage, an Early-Pandemic Variant. [PDF]

Comput Struct Biotechnol J
Chung HC, Jin Y, Kim SJ, Park SH, Chung HW, Hwang SJ, Ko SH, Nguyen VG, Lee JM.   +8 more
europepmc   +1 more source

Reprogramming of lipid metabolism by ORF3a-induced microlipophagy enhances biogenesis of SARS-CoV-2 replication organelle. [PDF]

PLoS Pathog
Li Z, Hui X, Zheng M, He Z, Huai W, Ding B, Jin M, Qin Y, Chen M.   +8 more
europepmc   +1 more source

Distinct mutational landscapes and phylogenomic insights of the SARS-CoV-2 delta variant in Pakistan and India: Regional evolution, novel mutations, and epidemiological implications. [PDF]

PLoS One
Fiaz N, Basheer A, Zahoor I, Naveed S, Yaqub T.   +4 more
europepmc   +1 more source