Results 121 to 130 of about 61,131 (327)

A Systematic Review on Organ-on-a-Chip in PDMS or Hydrogel in Dentistry: An Update of the Literature

open access: yesGels
Organs-on-a-chip (OoCs) are microfluidic devices constituted by PDMS or hydrogel in which different layers of cells are separated by a semipermeable membrane.
Tania Vanessa Pierfelice   +8 more
doaj   +1 more source

Quantum Emitters in Hexagonal Boron Nitride: Principles, Engineering and Applications

open access: yesAdvanced Functional Materials, EarlyView.
Quantum emitters in hexagonal boron nitride have emerged as a promising candidate for quantum information science. This review examines the fundamentals of these quantum emitters, including their level structures, defect engineering, and their possible chemical structures.
Thi Ngoc Anh Mai   +8 more
wiley   +1 more source

Therapeutic biomaterials based on extracellular vesicles: classification of bio-engineering and mimetic preparation routes [PDF]

open access: yes, 2018
This work was supported by the Ministerio de Economía y Competitividad (MINECO, Spain), under the Grant CTQ2013-47396-R. This study was also financed by the Consejería de Economía y Empleo del Principado de Asturias (Plan de Ciencia, Tecnología e ...
Blanco López, María del Carmen   +4 more
core   +2 more sources

Melanoma-on-a-chip model for anticancer drug injecting delivery method

open access: yesSLAS Technology
The pharmaceutical and cosmetic industries are encountering a challenge in adopting new study models for product development. there has been a growing interest in organ-on-a-chip systems, and particularly for generating skin models.
Pedro Herreros   +3 more
doaj   +1 more source

Human-Derived Organ-on-a-Chip for Personalized Drug Development.

open access: yesCurrent pharmaceutical design, 2019
To reduce the required capital and time investment in the development of new pharmaceutical agents, there is an urgent need for preclinical drug testing models that are predictive of drug response in human tissues or organs.
Yasamin A. Jodat   +7 more
semanticscholar   +1 more source

Synchrotron Radiation for Quantum Technology

open access: yesAdvanced Functional Materials, EarlyView.
Materials and interfaces underpin quantum technologies, with synchrotron and FEL methods key to understanding and optimizing them. Advances span superconducting and semiconducting qubits, 2D materials, and topological systems, where strain, defects, and interfaces govern performance.
Oliver Rader   +10 more
wiley   +1 more source

Living Cell Microarrays: An Overview of Concepts [PDF]

open access: yes, 2016
Living cell microarrays are a highly efficient cellular screening system. Due to the low number of cells required per spot, cell microarrays enable the use of primary and stem cells and provide resolution close to the single-cell level.
Jonczyk, Rebecca   +5 more
core   +3 more sources

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

In vitro tissue microarrays for quick and efficient spheroid characterisation [PDF]

open access: yes, 2018
Three-dimensional in vitro microphysiological cultures, such as spheroids and organoids, promise increased patient relevance and therapeutic predictivity compared to reductionist cell monolayers.
A. M. Grabowska, D. P. Ivanov, Subik K.
core   +2 more sources

Small Force, Big Impact: Next Generation Organ-on-a-Chip Systems Incorporating Biomechanical Cues

open access: yesFrontiers in Physiology, 2018
Mechanobiology-on-a-chip is a growing field focusing on how mechanical inputs modulate physico-chemical output in microphysiological systems. It is well known that biomechanical cues trigger a variety of molecular events and adjustment of mechanical ...
Ece Ergir   +14 more
doaj   +1 more source

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