Results 21 to 30 of about 67,848,505 (299)
Cytostretch, an Organ-on-Chip Platform [PDF]
Micromachines, 2016 Organ-on-Chips (OOCs) are micro-fabricated devices which are used to culture cells in order to mimic functional units of human organs. The devices are designed to simulate the physiological environment of tissues in vivo. Cells in some types of OOCs can be stimulated in situ by electrical and/or mechanical actuators.
Nikolas Gaio +7 more
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Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2022 Microfluidic chip systems have been an area of interest for lab-on-a-chip and organ-on-a-chip studies in recent years. These chips have many advantages such as high efficiency, low sample consumption, fast analysis, durability and low cost.
Fatma Doğan Guzel +2 more
doaj +1 more source
Microfluidic Organ-on-a-Chip Devices for Liver Disease Modeling In Vitro
Micromachines, 2022 Mortality from liver disease conditions continues to be very high. As liver diseases manifest and progress silently, prompt measures after diagnosis are essential in the treatment of these conditions.
Perizat Kanabekova +2 more
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Modular Microphysiological System for Modeling of Biologic Barrier Function
Frontiers in Bioengineering and Biotechnology, 2020 Microphysiological systems, also known as organs-on-chips, are microfluidic devices designed to model human physiology in vitro. Polydimethylsiloxane (PDMS) is the most widely used material for organs-on-chips due to established microfabrication methods,
Matthew Ishahak +10 more
doaj +1 more source
Microfluidic Liver-on-a-Chip for Preclinical Drug Discovery
Pharmaceutics, 2023 Drug discovery is an expensive, long, and complex process, usually with a high degree of uncertainty. In order to improve the efficiency of drug development, effective methods are demanded to screen lead molecules and eliminate toxic compounds in the ...
Jingyu Fu, Hailong Qiu, Cherie S. Tan
doaj +1 more source
, 2022 S.3963-3978Organ-on-chip (OoC) systems have become a promising tool for personalized medicine and drug development with advantages over conventional animal models and cell assays.
Rogal, Julia +8 more
core +1 more source
Organ-on-Chip In Development:Towards a roadmap for Organs-on-Chip
ALTEX, 2019 Organ-on-Chip is a game-changing technology born from the convergence of tissue engineering and microfluidic technology. Organ-on-Chip devices (OoCs) are expected to offer effective solutions to persisting problems in drug development and personalized disease treatments.
M. Mastrangeli +3 more
openaire +6 more sources
Emergence of microfluidics for next generation biomedical devices
Biosensors and Bioelectronics: X, 2022 The attention in lab-on-a-chip devices with their potent application in medical engineering has prolonged swiftly over the last ten years. Travelling through the technology development, innovative microfluidics devices shown enormous potential to lift ...
Subham Preetam +7 more
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Organs-on-chips: a decade of innovation
Trends in Biotechnology, 2023 Recreating 'living organs' with groundbreaking organ-on-a-chip (OOC) technologies is facilitating a new era of drug discovery. Studies by Huh et al. and Ronaldson-Bouchard et al. underscore advances made over a decade, spanning single organ functionality to interconnected organs, that enable examination of drug toxicities and disease pathogenesis in ...
Carly Strelez +2 more
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Micromachines, 2021 Glioma, as an aggressive type of cancer, accounts for virtually 80% of malignant brain tumors. Despite advances in therapeutic approaches, the long-term survival of glioma patients is poor (it is usually fatal within 12–14 months).
Merve Ustun +4 more
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