Results 11 to 20 of about 69,325 (340)

Oncoimmunology Meets Organs-on-Chip [PDF]

open access: yesFrontiers in Molecular Biosciences, 2021
Oncoimmunology represents a biomedical research discipline coined to study the roles of immune system in cancer progression with the aim of discovering novel strategies to arm it against the malignancy.
Fabrizio Mattei   +8 more
doaj   +5 more sources

3D bioprinted organ‐on‐chips

open access: yesAggregate, 2023
Organ‐on‐a‐chip (OOC) platforms recapitulate human in vivo‐like conditions more realistically compared to many animal models and conventional two‐dimensional cell cultures.
Sajjad Rahmani Dabbagh   +5 more
doaj   +6 more sources

Modeling the Effects of Protracted Cosmic Radiation in a Human Organ-on-Chip Platform. [PDF]

open access: yesAdv Sci (Weinh)
Galactic cosmic radiation (GCR) is one of the most serious risks posed to astronauts during missions to the Moon and Mars. Experimental models capable of recapitulating human physiology are critical to understanding the effects of radiation on human ...
Tavakol DN   +17 more
europepmc   +2 more sources

Organ-on-chip [PDF]

open access: yes, 2021
Lo sviluppo di nuovi farmaci è un processo lungo, costoso ed attualmente poco efficiente. La causa di questa scarsa efficienza risiede, principalmente, nella scarsa efficienza ed accuratezza delle attuali metodologie di ricerca preclinica, basate su ...
Caragnano, Giusi   +5 more
core   +3 more sources

Organ-on-Chip systems as a model for nanomedicine

open access: yesNanoscale, 2023
Nanomedicine is giving rise to increasing numbers of successful drugs, including cancer treatments, molecular imaging agents, and novel vaccine formulations.
M. Stavrou   +3 more
semanticscholar   +3 more sources

Advances in modeling periodontal host-microbe interactions: insights from organotypic and organ-on-chip systems.

open access: yesLab Chip
Periodontal disease, a chronic inflammatory condition affecting the supporting structures of teeth, is driven by an imbalanced interaction between the periodontal microbiota and the host inflammatory response. Beyond its local impact, periodontal disease
Makkar H, Sriram G.
europepmc   +2 more sources

Developer’s Guide to an Organ-on-Chip Model

open access: yesACS Biomaterials Science & Engineering, 2022
Over the past decade, organ-on-chip research has been one of the most prolific areas of the entire field of tissue engineering. The development of organ-on-chip models requires an integrated interdisciplinary approach merging technologies and concepts ...
Julia Rogal   +2 more
semanticscholar   +3 more sources

Organs-on-chips: into the next decade [PDF]

open access: yesNature Reviews Drug Discovery, 2020
Organs-on-chips (OoCs), also known as microphysiological systems or 'tissue chips' (the terms are synonymous), have attracted substantial interest in recent years owing to their potential to be informative at multiple stages of the drug discovery and development process.
Lucie A. Low   +4 more
openaire   +3 more sources

NeuriTES. Monitoring neurite changes through transfer entropy and semantic segmentation in bright-field time-lapse microscopy

open access: yesPatterns, 2021
Summary: One of the most challenging frontiers in biological systems understanding is fluorescent label-free imaging. We present here the NeuriTES platform that revisits the standard paradigms of video analysis to detect unlabeled objects and adapt to ...
Arianna Mencattini   +12 more
doaj   +1 more source

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