Results 61 to 70 of about 68,048 (303)

Guiding organs-on-chips towards applications: a balancing act between integration of advanced technologies and standardization

Frontiers in Lab on a Chip Technologies
Organs-on-chips (OoC) are in vitro models that emulate key functionalities of tissues or organs in a miniaturized and highly controlled manner. Due to their high versatility, OoC have evolved as promising alternatives to animal testing for a more ...
J. Meneses, F. Conceição, A. D. van der Meer, A. D. van der Meer, S. de Wit, L. Moreira Teixeira, L. Moreira Teixeira   +6 more
doaj   +1 more source

Retina-on-chip: engineering functional in vitro models of the human retina using organ-on-chip technology.

Lab on a Chip
The retina is a complex and highly metabolic tissue in the back of the eye essential for human vision. Retinal diseases can lead to loss of vision in early and late stages of life, significantly affecting patients' quality of life.
Tarek Gensheimer, D. Veerman, E. V. van Oosten, L. Segerink, A. Garanto, A. D. van der Meer   +5 more
semanticscholar   +1 more source

Bioprinting on Organ-on-Chip: Development and Applications

Biosensors, 2022
Organs-on-chips (OoCs) are microfluidic devices that contain bioengineered tissues or parts of natural tissues or organs and can mimic the crucial structures and functions of living organisms.
M. Chliara, S. Elezoglou, I. Zergioti
semanticscholar   +1 more source

Cells in the 3D biomatrix on-chip: better mimicking the real micro-physiological system

Next Materials
Recent advances in microfluidic technology and biomaterial science have augmented the use of organ-on-chip (OoC) technology to closely mimic the human pathophysiology.
Michele D’Orazio, Joanna Filippi, Gianni Antonelli, Giorgia Curci, Paola Casti, Arianna Mencattini, Gianluca Cidonio, Eugenio Martinelli   +7 more
doaj   +1 more source

Organ-on-Chip Approaches for Intestinal 3D In Vitro Modeling

Cellular and Molecular Gastroenterology and Hepatology, 2021
The intestinal epithelium has one of the highest turnover rates in the human body, which is supported by intestinal stem cells. Culture models of intestinal physiology have been evolving to incorporate different tissue and microenvironmental elements ...
J. Pimenta, Ricardo Ribeiro, Raquel Almeida, P. Costa, M. A. da Silva, B. Pereira   +5 more
semanticscholar   +1 more source

Organs-on-chips: latest developments

Microphysiological Systems, 2019
Welcome to the collection of the current must-read open-access papers in the field of organs-on-chips that have become available in the second half of 2018. This quarterly editorial column will be compiled by Dr. Andries D. van der Meer, University of Twente, The Netherlands.
openaire   +1 more source

Organ-on-chip technology: Opportunities and challenges

Biotechnology Notes
Organ-on-chip (OOC) technology is an innovative approach that reproduces human organ structures and functions on microfluidic platforms, offering detailed insights into intricate physiological processes.
S. Srivastava, Guo Wei Foo, Nikhil Aggarwal, M. Chang   +3 more
semanticscholar   +1 more source

Sociodemographic Factors Associated With Later Stage at Diagnosis of Pediatric Germ Cell Tumors: A Report From Children's Oncology Group Registries ACCRN07 and APEC14B1

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Germ cell tumors (GCTs) often arise in the ovaries and testes (extracranial) but can also develop in the brain (intracranial). We examined the relationship of individual, family, and community‐level socioeconomic status (SES) with stage of disease at diagnosis in a cohort of pediatric patients with GCT from Children's Oncology Group
Heydon K. Kaddas, Judy Y. Ou, Todd Alonzo, Logan G. Spector, Negar Fallahazad, Emily Owens, Anne C. Kirchhoff, Adam L. Green   +7 more
wiley   +1 more source

Cold Atmospheric Plasma as a Potential Disease-Modifying Therapy for Osteoarthritis

Biomedicines
Osteoarthritis (OA) is a disabling joint disease characterised by cartilage degradation, synovial inflammation, and subchondral bone remodelling. Furthermore, catabolic inflammatory processes as well as dysregulated cellular signalling and oxidative ...
Vinay Kumar, Fiona O’Neill, Emma J. Murphy, Declan M. Devine, Liam O’Neill, Niamh Fahy   +5 more
doaj   +1 more source

Microsensor systems for cell metabolism - from 2D culture to organ-on-chip (2019-2024).

Lab on a Chip
Cell cultures, organs-on-chip and microphysiological systems become increasingly relevant as in vitro models, e.g., in drug development, disease modelling, toxicology or cancer research.
Johannes Dornhof, J. Kieninger, S. J. Rupitsch, A. Weltin   +3 more
semanticscholar   +1 more source