Results 71 to 80 of about 69,325 (340)
Micromachines, 2022 The PDMS-based microfluidic organ-on-chip platform represents an exciting paradigm that has enjoyed a rapid rise in popularity and adoption. A particularly promising element of this platform is its amenability to rapid manufacturing strategies, which can
T. Cameron +8 more
semanticscholar +1 more source
Microelectromechanical Organs-on-Chip
2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers), 2021 Stemming from the convergence of tissue engineering and microfluidics, organ-on-chip (OoC) technology can reproduce in vivo-like dynamic microphysiological environments for tissues in vitro. The possibility afforded by OoC devices of realistic recapitulation of tissue and organ (patho)physiology may hold the key to bridge the current translational gap ...
Mastrangeli, Massimo (author) +7 more
openaire +3 more sources
A planar surface acoustic wave micropump for closed-loop microfluidics [PDF]
, 2017 We have designed and characterized a simple Rayleigh-surface acoustic wave-based micropump, integrated directly with a fully enclosed 3D microfluidic system, which improves significantly the pumping efficiency within a coupled fluid whilst maintaining ...
A. J. Smith +4 more
core +2 more sources
Physiologically relevant organs on chips [PDF]
Biotechnology Journal, 2013 AbstractRecent advances in integrating microengineering and tissue engineering have generated promising microengineered physiological models for experimental medicine and pharmaceutical research. Here we review the recent development of microengineered physiological systems, or also known as “ogans‐on‐chips”, that reconstitute the physiologically ...
Kyungsuk, Yum +3 more
openaire +2 more sources
Toward modeling the human nervous system in a dish: recent progress and outstanding challenges [PDF]
, 2017 Studying the cellular and molecular bases governing development, and normal and abnormal functions of the human CNS is hampered by its complexity and the very limited possibility of experimentally manipulating it in vivo.
Ferretti, P, Vagaska, B
core +1 more source
Organ on chip: building a roadmap towards standardisation [PDF]
, 2021 For Organ on Chip (OoC) there is a widespread opinion, that standardisation is an important enabler for innovation, supporting the development and application of devices through performance assessment and benchmarking, interoperability, and qualification
BATISTA LEITE Sofia +8 more
core +1 more source
Liver organ-on-chip models for toxicity studies and risk assessment.
Lab on a Chip, 2022 The liver is a key organ that plays a pivotal role in metabolism and ensures a variety of functions in the body, including homeostasis, synthesis of essential components, nutrient storage, and detoxification.
Taha Messelmani +6 more
semanticscholar +1 more source
Microfluidic Platforms to Unravel Mysteries of Alzheimer’s Disease: How Far Have We Come?
Life, 2021 Alzheimer’s disease (AD) is a significant health concern with enormous social and economic impact globally. The gradual deterioration of cognitive functions and irreversible neuronal losses are primary features of the disease.
Pragya Prasanna +12 more
doaj +1 more source
On the Road to Accurate Biomarkers for Cardiometabolic Diseases by Integrating Precision and Gender Medicine Approaches [PDF]
, 2019 The need to facilitate the complex management of cardiometabolic diseases (CMD) has led to the detection of many biomarkers, however, there are no clear explanations of their role in the prevention, diagnosis or prognosis of these diseases.
Argano, Vincenzo +5 more
core +1 more source
Bioprinting on Organ-on-Chip: Development and Applications
Biosensors, 2022 Organs-on-chips (OoCs) are microfluidic devices that contain bioengineered tissues or parts of natural tissues or organs and can mimic the crucial structures and functions of living organisms.
M. Chliara, S. Elezoglou, I. Zergioti
semanticscholar +1 more source