Results 21 to 30 of about 1,034,083 (358)

Acylated and unacylated ghrelin directly regulate ß-3 stimulated lipid turnover in rodent subcutaneous and visceral adipose tissue ex vivo but not in vivo

open access: yesAdipocyte, 2019
Ghrelin has garnered interest as a gut-derived regulator of lipid metabolism, beyond its classical roles in driving appetite and growth hormone release.
Daniel T. Cervone   +3 more
doaj   +1 more source

A novel and cost-effective ex vivo orthotopic model for the study of human breast cancer in mouse mammary gland organ culture

open access: yesBiology Open, 2020
Mouse mammary organ culture (MMOC) is used to evaluate the efficacy of chemopreventive agents against the development of carcinogen-induced preneoplastic lesions and is highly correlative to in vivo carcinogenesis models. Here, we developed a new ex vivo
Akash Gupta   +10 more
doaj   +1 more source

Integration of systems biology with organs-on-chips to humanize therapeutic development [PDF]

open access: yes, 2017
"Mice are not little people" - a refrain becoming louder as the gaps between animal models and human disease become more apparent. At the same time, three emerging approaches are headed toward integration: powerful systems biology analysis of cell-cell ...
Chen, Wen Li   +6 more
core   +1 more source

Органная культура Сибири XIX - первой четверти XX века в контексте конфессиональной и художественной деятельности переселенцев западно-христианского вероисповедания

open access: yesВестник музыкальной науки, 2014
В статье автор обращается к одной из актуальных и неизученных проблем музыкального сибиреведения, связанной с историей органной культуры в Сибири дореволюционного времени и ролью представителей римско-католической и евангелическо-лютеранской конфессий в ...
Пронина, Анна Николаевна
doaj   +1 more source

Ex vivo intervertebral disc cultures: degeneration-induction methods and their implications for clinical translation [PDF]

open access: yesEuropean Cells & Materials, 2023
Because low back pain is frequently a result of intervertebral disc degeneration (IVDD), strategies to regenerate or repair the IVD are currently being investigated.
E Salzer   +11 more
doaj   +1 more source

Acetylsalicylic acid interferes with embryonic kidney growth and development by a prostaglandin-independent mechanism [PDF]

open access: yes, 2017
AIM: To evaluate the effects of the non-selective, non-steroidal anti-inflammatory drug (NSAID) acetylsalicylic acid (ASA), on ex vivo embryonic kidney growth and development.
Elmes, Matthew J.   +3 more
core   +2 more sources

Observation of the Epithelial Cell Behavior in the Nasal Septum During Primary Palate Closure in Mice

open access: yesFrontiers in Physiology, 2020
Epithelial fusion is critical in palatogenesis, and incomplete fusion results in various type of facial cleft, depending on the region that fails to fuse.
Sayuri Yamamoto   +11 more
doaj   +1 more source

A dynamic multi-organ-chip for long-term cultivation and substance testing proven by 3D human liver and skin tissue co-culture [PDF]

open access: yes, 2013
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence
Brincker, Sven   +11 more
core   +2 more sources

Cultural Entrepreneurship: Between-Organization Cultural Isomorphism and Within-Organization Culture Shaping [PDF]

open access: yesSage Open, 2020
Cultural entrepreneurship is a process that focuses on entrepreneurial resources, identifies and legitimates new startups, and improves organizational performance. Although scholars of this subject have viewed entrepreneurs as cultural agents, for example, who either strike a balance between cultural resources and constraints or decouple their ...
Seungdoe Lee, Goo Hyeok Chung
openaire   +2 more sources

Evaluation of interface quality in organ-cultured lamellar corneal transplants [PDF]

open access: yes, 2012
Background: With increasing numbers of lamellar keratoplasties, eye banks are challenged to deliver precut lamellar donor tissue. In Europe, the most common technique of corneal storage is organ culture which requires a deswelling process before surgical
Grüterich, Martin   +7 more
core   +1 more source

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