Results 91 to 100 of about 2,755,367 (283)

Inner ear tissue preservation by rapid freezing: improving fixation by high-pressure freezing and hybrid methods [PDF]

open access: yes, 2014
In the preservation of tissues in as ‘close to life’ state as possible, rapid freeze fixation has many benefits over conventional chemical fixation. One technique by which rapid freeze-fixation can be achieved, high pressure freezing (HPF), has been ...
A. Bullen   +47 more
core   +1 more source

Multicargo Porous Cochlear Electrode Coating for Antifibrosis After Cochlear Implantation

open access: yesAdvanced Science, EarlyView.
This study presents a novel porous drug‐loading coating for cochlear electrodes, utilizing MA‐PDMS infused with GelMA hydrogel containing dexamethasone and MXene nanoparticles. The coating enhances biocompatibility, enables sustained drug release, reduces fibrosis, and preserves residual hearing post‐CI.
Lei Ren   +15 more
wiley   +1 more source

Six1 is essential for differentiation and patterning of the mammalian auditory sensory epithelium.

open access: yesPLoS Genetics, 2017
The organ of Corti in the cochlea is a two-cell layered epithelium: one cell layer of mechanosensory hair cells that align into one row of inner and three rows of outer hair cells interdigitated with one cell layer of underlying supporting cells along ...
Ting Zhang   +3 more
doaj   +1 more source

Semistable 3-fold flips [PDF]

open access: yesarXiv, 1995
We piece together ingredients, which are well known and documented in the literature, into a new proof of the existence of semistable 3-fold ...
arxiv  

Styrene enhances the noise induced oxidative stress in the cochlea and affects differently mechanosensory and supporting cells [PDF]

open access: yes, 2016
Experimental and human investigations have raised the level of concern about the potential ototoxicity of organic solvents and their interaction with noise.
Eramo, Sara Letizia Maria   +6 more
core   +1 more source

ACETYLCHOLINESTERASE IN THE ORGAN OF CORTI

open access: yesACTA HISTOCHEMICA ET CYTOCHEMICA, 1971
Histochemical investigation of acetylcholinesterase in the organ of Corti has been carried out by means of the Karnovsky's method. Acetylcholinesterase is located on the bottom of outer hair cells, tunnel radial fibers (upper), tunnel spiral bundle and inner spiral bundle.
openaire   +2 more sources

Small Extracellular Vesicles Orchestrate Cisplatin‐Induced Ototoxicity: Potential Biomarker and Targets Discovery

open access: yesAdvanced Science, EarlyView.
Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai   +14 more
wiley   +1 more source

On the origins of the compressive cochlear nonlinearity [PDF]

open access: yes, 2011
Various simple mathematical models of the dynamics of the organ of Corti in the mammalian cochlea are analysed. The models are assessed against their ability to explain the compressive nonlinear response of the basilar membrane.
Champneys, AR   +5 more
core  

Visualization of the Spiral Ganglion Neuron in Vivo Using a Novel 177Lu Nuclear Molecule Label

open access: yesAdvanced Science, EarlyView.
The study developed and validated a radionuclide‐labeled anti‐VGLUT1 antibody probe for the first nuclear imaging of cochlear spiral ganglion neurons (SGNs) in vivo. This approach may provide aid in screening candidates suitable for CI surgery by quantifying the number of surviving SGNs, and predicting the potential for postoperative hearing ...
Chenyang Kong   +11 more
wiley   +1 more source

Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development [PDF]

open access: yes, 2008
Background During mouse development, the precursor cells that give rise to the auditory sensory organ, the organ of Corti, are specified prior to embryonic day 14.5 (E14.5).
Chen, Ping   +5 more
core   +3 more sources

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