Quantitative High-Resolution Cellular Map of the Organ of Corti
Cell Reports, 2015 The organ of Corti harbors highly specialized sensory hair cells and surrounding supporting cells that are essential for the sense of hearing. Here, we report a single cell gene expression data analysis and visualization strategy that allows for the ...
Jörg Waldhaus +2 more
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Rab11a Is Essential for the Development and Integrity of the Stereocilia and Kinocilia in the Mammalian Organ of Corti. [PDF]
eNeuro, 2023 Knapp L +7 more
europepmc +3 more sources
Targeted cell interconversions reveal inner hair cell control of organ of Corti cytoarchitecture. [PDF]
Sci AdvGarcía-Gómez I +10 more
europepmc +2 more sources
Otoacoustic emissions reveal the micromechanical role of organ-of-Corti cytoarchitecture in cochlear amplification. [PDF]
Proc Natl Acad Sci U S A, 2023 Shera CA, Altoè A.
europepmc +3 more sources
MnTBAP, a peroxynitrite scavenger, attenuates cisplatin-induced apoptosis and cytotoxicity in organ of Corti cells. [PDF]
Toxicol RepShahab M +4 more
europepmc +2 more sources
Unbalanced bidirectional radial stiffness gradients within the organ of Corti promoted by TRIOBP. [PDF]
Proc Natl Acad Sci U S A, 2022 Babahosseini H +10 more
europepmc +3 more sources
Cochlea cell-specific marker expression upon in vitro Hes1 knockdown [PDF]
Brazilian Journal of Medical and Biological Research, 2021 NOTCH pathway proteins, including the transcriptional factor HES1, play crucial roles in the development of the inner ear by means of the lateral inhibition mechanism, in which supporting cells have their phenotype preserved while they are prevented from
A.C. Batissoco +9 more
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Dysferlin Protein-Protein Interaction Pathways in the Organ of Corti and Spiral Ganglion Intersect with Alzheimer's Protein Pathways. [PDF]
Int J Mol SciDrescher MJ +4 more
europepmc +3 more sources
Estradiol protects hair cells from cisplatin-induced ototoxicity via Nrf2 activation
Redox Report, 2023 Cisplatin-induced ototoxicity is caused by reactive oxygen species. It has been recognized that estradiol (E2) regulates redox balance. However, little is known about the protective mechanisms of E2 against cisplatin-induced ototoxicity.
Masahiro Adachi +5 more
doaj +1 more source
Bmi1 Loss in the Organ of Corti Results in p16ink4a Upregulation and Reduced Cell Proliferation of Otic Progenitors In Vitro. [PDF]
PLoS ONE, 2016 The mature mammalian organ of Corti does not regenerate spontaneously after injury, mainly due to the absence of cell proliferation and the depletion of otic progenitors with age.
Mohamed Bassiouni +4 more
doaj +1 more source