Results 21 to 30 of about 166,078,283 (220)
, 2011 Organ of Corti is an experimental instrument that filters the sounds around it into new listening experiences. The piece invokes the disciplines of music; sound, land-, and installation art, acoustic ecology, and acoustics, offering insights in these ...
Prior, David, Crow, Frances
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Cochlea cell-specific marker expression upon in vitro Hes1 knockdown [PDF]
Brazilian Journal of Medical and Biological Research, 2021 NOTCH pathway proteins, including the transcriptional factor HES1, play crucial roles in the development of the inner ear by means of the lateral inhibition mechanism, in which supporting cells have their phenotype preserved while they are prevented from
A.C. Batissoco +9 more
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Estradiol protects hair cells from cisplatin-induced ototoxicity via Nrf2 activation
Redox Report, 2023 Cisplatin-induced ototoxicity is caused by reactive oxygen species. It has been recognized that estradiol (E2) regulates redox balance. However, little is known about the protective mechanisms of E2 against cisplatin-induced ototoxicity.
Masahiro Adachi +5 more
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Cochlear Development; New Tools and Approaches
Frontiers in Cell and Developmental Biology, 2022 The sensory epithelium of the mammalian cochlea, the organ of Corti, is comprised of at least seven unique cell types including two functionally distinct types of mechanosensory hair cells.
Matthew W. Kelley
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mTOR Signaling in BDNF-Treated Guinea Pigs after Ototoxic Deafening
Biomedicines, 2022 The mammalian target of rapamycin (mTOR) signaling plays a critical role in cell homeostasis, growth and survival. Here, we investigated the localization of the main mTOR signaling proteins in the organ of Corti of normal-hearing and deafened guinea pigs,
Annamaria Tisi +4 more
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STAR Protocols, 2021 Summary: This protocol describes the preparation of the mouse organ of Corti for RNAscope, immunolabeling, confocal microscopy, and quantitative image analysis to examine transcript and protein localization, sensory hair cells, and synapses.
Daniel O.J. Reijntjes +3 more
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PLoS Biology, 2012 A large proportion of age-related hearing loss is caused by loss or damage to outer hair cells in the organ of Corti. The organ of Corti is the mechanosensory transducing apparatus in the inner ear and is composed of inner hair cells, outer hair cells ...
Sung-Ho Huh +3 more
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Disease Models & Mechanisms, 2018 Mutations in the GJB2 gene [which encodes connexin 26 (Cx26)] are the most common causes of hereditary hearing loss in humans, and previous studies showed postnatal development arrest of the organ of Corti in different Cx26-null mouse models.
Sen Chen +7 more
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A multiscale model of the organ of Corti [PDF]
Journal of Mechanics of Materials and Structures, 2009 The organ of Corti is the sensory epithelium in the cochlea of the inner ear. It is modeled as a shell-of-revolution structure with continuous and discrete components. Our recent work has been on the inclusion of the viscous fluid. Measurements from various laboratories provide the opportunity to refocus on the elastic properties.
Charles R, Steele +2 more
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Primary Culture and Plasmid Electroporation of the Murine Organ of Corti [PDF]
, 2010 In all mammals, the sensory epithelium for audition is located along the spiraling organ of Corti that resides within the conch shaped cochlea of the inner ear (fig 1).
Mark Parker +5 more
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